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Table 1 Clinical characteristics of 1920 diabetic patients

From: Mitochondrial 8-hydroxy-2′-deoxyguanosine and coronary artery disease in patients with type 2 diabetes mellitus

Variables

All participants

After PS matching

Obstructive CAD

(N = 1054)

Non-CAD

(N = 866)

Pa

Obstructive CAD

(N = 673)

Non-CAD

(N = 673)

Pa

Age, years

62.8 ± 9.6

61.1 ± 10.7

< 0.001

62.3 ± 9.5

62.3 ± 10.8

0.977

Male, n (%)

583 (55.3)

480 (55.4)

0.960

360 (53.5)

373 (55.4)

0.477

BMI, mean (SD), kg/m2

25.2 ± 4.0

24.3 ± 2.6

< 0.001

24.7 ± 3.9

24.5 ± 2.6

0.204

BMI categories

 Normal

540 (51.2)

494 (57.0)

< 0.001

412 (61.2)

396 (58.8)

0.613

 Overweight

372 (35.3)

317 (36.6)

 

116 (17.2)

118 (17.6)

 

 Obese

142 (13.5)

55 (6.4)

 

145 (21.6)

159 (23.6)

 

Smoking, n (%)

 Never smoker

582 (55.2)

555 (64.1)

< 0.001

382 (56.8)

358 (53.2)

0.157

 Former smoker

168 (15.9)

130 (15.0)

 

231 (34.3)

264 (39.2)

 

 Current smoker

304 (28.9)

181 (20.9)

 

60 (8.9)

51 (7.6)

 

Alcohol drinkers, n (%)

343 (32.5)

248 (28.6)

0.065

210 (31.2)

196 (29.1)

0.406

FPG, mmol/L

7.3 ± 2.0

6.7 ± 1.8

< 0.001

7.0 ± 1.6

6.9 ± 2.0

0.386

HbA1c, (%)

8.1 ± 1.8

7.9 ± 1.7

0.031

8.0 ± 1.8

8.0 ± 1.7

0.779

Diabetes duration, years

10.3 ± 5.4

9.9 ± 5.7

0.110

10.1 ± 5.4

9.7 ± 5.7

0.105

Diabetes management

 Lifestyle modification

291 (27.6)

255 (29.4)

0.566

200 (29.7)

199 (29.6)

0.500

 Oral agents only

332 (31.5)

283 (32.7)

 

206 (30.6)

229 (34.0)

 

 Insulin only

275 (26.1)

214 (24.7)

 

166 (24.7)

157 (23.3)

 

 Oral agents and insulin

156 (14.8)

114 (13.2)

 

101 (15.0)

88 (13.1)

 

Dyslipidemia, n (%)

334 (31.7)

166 (19.2)

< 0.001

164 (24.4)

158 (23.5)

0.701

Cholesterol, mmol/L

 TC, mmol/L

4.95 ± 0.91

4.80 ± 0.85

< 0.001

4.88 ± 0.90

4.85 ± 0.87

0.194

 LDL-c, mmol/L

3.28 ± 0.83

3.08 ± 0.68

< 0.001

3.16 ± 0.80

3.10 ± 0.67

0.123

 HDL-c, mmol/L

1.12 ± 0.15

1.16 ± 0.21

0.318

1.09 ± 0.15

1.12 ± 0.21

0.756

 TG, mmol/L

1.48 ± 0.85

1.36 ± 0.76

0.104

1.49 ± 0.84

1.43 ± 0.80

0.114

Hypertension, n (%)

619 (58.7)

338 (39.0)

< 0.001

330 (49.0)

318 (47.3)

0.513

Blood pressure

 SBP, mmHG

138.2 ± 21.4

134.8 ± 19.5

< 0.001

136.7 ± 25.0

135.4 ± 19.1

0.157

 DBP, mmHG

88.0 ± 18.4

85.1 ± 12.0

< 0.001

86.4 ± 18.1

85.9 ± 11.4

0.109

CRP, mg/L

1.57 ± 1.01

1.10 ± 0.86

< 0.001

1.34 ± 0.94

1.30 ± 0.87

0.400

D-dimer, mg/L

0.98 ± 0.93

0.91 ± 0.82

0.077

0.93 ± 0.95

0.91 ± 0.79

0.228

  1. Data are presented as the mean ± SD or n (%) as appropriate
  2. BMI body mass index, FPG fasting plasma glucose, HbA1c glycosylated haemoglobin, TC total cholesterol, LDL-c low-density lipoprotein cholesterol, HDL-c high-density lipoprotein cholesterol, TG triglycerides, SBP systolic blood pressure, DBP diastolic blood pressure, CRP C-reactive protein, CAD coronary artery disease, PS propensity score
  3. aP values were obtained from the student t test for continuous variables, and the Pearson χ2 test for categorical variables