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Table 1 Clinical characteristics of 1920 diabetic patients

From: Mitochondrial 8-hydroxy-2′-deoxyguanosine and coronary artery disease in patients with type 2 diabetes mellitus

VariablesAll participantsAfter PS matching
Obstructive CAD
(N = 1054)
Non-CAD
(N = 866)
PaObstructive CAD
(N = 673)
Non-CAD
(N = 673)
Pa
Age, years62.8 ± 9.661.1 ± 10.7< 0.00162.3 ± 9.562.3 ± 10.80.977
Male, n (%)583 (55.3)480 (55.4)0.960360 (53.5)373 (55.4)0.477
BMI, mean (SD), kg/m225.2 ± 4.024.3 ± 2.6< 0.00124.7 ± 3.924.5 ± 2.60.204
BMI categories
 Normal540 (51.2)494 (57.0)< 0.001412 (61.2)396 (58.8)0.613
 Overweight372 (35.3)317 (36.6) 116 (17.2)118 (17.6) 
 Obese142 (13.5)55 (6.4) 145 (21.6)159 (23.6) 
Smoking, n (%)
 Never smoker582 (55.2)555 (64.1)< 0.001382 (56.8)358 (53.2)0.157
 Former smoker168 (15.9)130 (15.0) 231 (34.3)264 (39.2) 
 Current smoker304 (28.9)181 (20.9) 60 (8.9)51 (7.6) 
Alcohol drinkers, n (%)343 (32.5)248 (28.6)0.065210 (31.2)196 (29.1)0.406
FPG, mmol/L7.3 ± 2.06.7 ± 1.8< 0.0017.0 ± 1.66.9 ± 2.00.386
HbA1c, (%)8.1 ± 1.87.9 ± 1.70.0318.0 ± 1.88.0 ± 1.70.779
Diabetes duration, years10.3 ± 5.49.9 ± 5.70.11010.1 ± 5.49.7 ± 5.70.105
Diabetes management
 Lifestyle modification291 (27.6)255 (29.4)0.566200 (29.7)199 (29.6)0.500
 Oral agents only332 (31.5)283 (32.7) 206 (30.6)229 (34.0) 
 Insulin only275 (26.1)214 (24.7) 166 (24.7)157 (23.3) 
 Oral agents and insulin156 (14.8)114 (13.2) 101 (15.0)88 (13.1) 
Dyslipidemia, n (%)334 (31.7)166 (19.2)< 0.001164 (24.4)158 (23.5)0.701
Cholesterol, mmol/L
 TC, mmol/L4.95 ± 0.914.80 ± 0.85< 0.0014.88 ± 0.904.85 ± 0.870.194
 LDL-c, mmol/L3.28 ± 0.833.08 ± 0.68< 0.0013.16 ± 0.803.10 ± 0.670.123
 HDL-c, mmol/L1.12 ± 0.151.16 ± 0.210.3181.09 ± 0.151.12 ± 0.210.756
 TG, mmol/L1.48 ± 0.851.36 ± 0.760.1041.49 ± 0.841.43 ± 0.800.114
Hypertension, n (%)619 (58.7)338 (39.0)< 0.001330 (49.0)318 (47.3)0.513
Blood pressure
 SBP, mmHG138.2 ± 21.4134.8 ± 19.5< 0.001136.7 ± 25.0135.4 ± 19.10.157
 DBP, mmHG88.0 ± 18.485.1 ± 12.0< 0.00186.4 ± 18.185.9 ± 11.40.109
CRP, mg/L1.57 ± 1.011.10 ± 0.86< 0.0011.34 ± 0.941.30 ± 0.870.400
D-dimer, mg/L0.98 ± 0.930.91 ± 0.820.0770.93 ± 0.950.91 ± 0.790.228
  1. Data are presented as the mean ± SD or n (%) as appropriate
  2. BMI body mass index, FPG fasting plasma glucose, HbA1c glycosylated haemoglobin, TC total cholesterol, LDL-c low-density lipoprotein cholesterol, HDL-c high-density lipoprotein cholesterol, TG triglycerides, SBP systolic blood pressure, DBP diastolic blood pressure, CRP C-reactive protein, CAD coronary artery disease, PS propensity score
  3. aP values were obtained from the student t test for continuous variables, and the Pearson χ2 test for categorical variables