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Table 5 Type 2 diabetes only—all-risk for atrial fibrillation by 1.0% (10 mmol/mol) of time updated mean HbA1c

From: Risk of atrial fibrillation in persons with type 2 diabetes and the excess risk in relation to glycaemic control and renal function: a Swedish cohort study

 

P-value

HR

Lower 95% CI

Upper 95% CI

Overall

 Model 1

< 0.0001

1.038

1.029

1.048

 Model 2

< 0.0001

1.030

1.021

1.039

 Model 3

< 0.0001

1.027

1.017

1.037

 Model 3A

< 0.0001

1.010

0.999

1.021

 Model 3B

< 0.0001

1.031

1.018

1.043

 Model 3C

< 0.0001

1.023

1.005

1.041

 Model 3D

< 0.0001

1.013

1.002

1.025

Male

 Model 1

< 0.0001

1.026

1.014

1.038

 Model 2

0.0024

1.019

1.007

1.031

 Model 3

0.0443

1.013

1.000

1.027

 Model 3A

0.4609

0.995

0.981

1.009

 Model 3B

0.0070

1.022

1.006

1.037

 Model 3C

0.1571

1.017

0.994

1.040

 Model 3D

0.4320

0.994

0.980

1.009

Female

 Model 1

< 0.0001

1.054

1.039

1.068

 Model 2

< 0.0001

1.044

1.030

1.059

 Model 3

< 0.0001

1.044

1.028

1.060

 Model 3A

0.0012

1.029

1.011

1.047

 Model 3B

< 0.0001

1.043

1.023

1.063

 Model 3C

0.0244

1.033

1.004

1.063

 Model 3D

< 0.0001

1.040

1.022

1.058

  1. Model 1: adjusted for time-updated age
  2. Model 2: model 1 additionally adjusted for born in Sweden, education level, baseline comorbidities (coronary heart disease, heart failure, valve disease, stroke, cancer)
  3. Model 3: model 2 additionally adjusted for time-updated diabetes duration
  4. Model 3A: model 3 additionally adjusted for time-updated mean systolic blood pressure, time-updated mean body mass index, time updated smoking status, time-updated status about blood pressure lowering medication
  5. Model 3B: model 3 additionally adjusted for time-updated mean high-density lipoprotein, time-updated mean low density lipoprotein, time-updated status about lipid lowering medication
  6. Model 3C: Model 3 additionally adjusted for time-updated insulin method
  7. Model 3D: model 3 additionally adjusted for time-updated albuminuria categories