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Table 3 Pairwise comparisons (with Bonferroni correction) for those endpoints with significant differences between the three treatments on ANOVA

From: Aspirin, clopidogrel and prasugrel monotherapy in patients with type 2 diabetes mellitus: a double-blind randomised controlled trial of the effects on thrombotic markers and microRNA levels

 Aspirin vs. clopidogrelAspirin vs. prasugrelClopidogrel vs. prasugrel
Mean difference (95% CI)pMean difference (95% CI)pMean difference (95% CI)p
Maximum platelet aggregation response (%)
AgonistConcentration 
 ADP1 μmol/L20.46 (16.33 to 24.58)< 0.00131.24 (26.79 to 35.68)< 0.00110.78 (7.34 to 14.22)< 0.001
2 μmol/L23.04 (17.17 to 29.91)< 0.00139.96 (35.75 to 44.18)< 0.00116.93 (12.48 to 21.00)< 0.001
5 μmol/L21.80 (16.01 to 27.59)< 0.00143.07 (38.54 to 47.60)< 0.00121.27 (16.75 to 25.80)< 0.001
10 μmol/L22.29 (15.97 to 28.61)< 0.00146.86 (41.39 to 52.32)< 0.00124.56 (28.98 to 20.14)< 0.001
20 μmol/L19.94 (13.71 to 26.14)< 0.00143.53 (38.57 to 48.49)< 0.00123.60 (19.34 to 27.83)< 0.001
 AA1 mmol/L− 56.86 (− 68.89 to − 44.82)< 0.001− 45.98 (− 56.77 to − 35.20)< 0.00110.87 (0.95 to 20.79)0.027
 Collagen2 μg/mL− 10.24 (− 16.52 to − 3.95)0.0011.86 (− 3.22 to 6.92)> 0.9912.09 (7.52 to 16.66)< 0.001
16 μg/mL0.62 (− 2.28 to 3.52)> 0.995.73 (2.71 to 8.74)< 0.0015.11 (1.48 to 8.74)0.003
Platelet P-selectin expression (%)
[ADP] μmol/L 
 0.35.87 (2.05 to 9.69)0.00112.52 (8.32 to 16.72)< 0.0016.65 (3.65 to 9.65)< 0.001
 113.00 (6.56 to 19.43)< 0.00122.23 (16.00 to 28.45)< 0.0019.23 (5.30 to 13.16)< 0.001
 314.27 (6.95 to 21.58)< 0.00127.37 (19.63 to 35.11)< 0.00113.10 (8.19 to 18.01)< 0.001
 1017.28 (9.90 to 24.66)< 0.00129.95 (22.17 to 37.74)< 0.00112.67 (7.55 to 17.80)< 0.001
 3018.02 (9.82 to 26.22)< 0.00130.97 (23.13 to 38.81)< 0.00112.95 (7.22 to 18.68)< 0.001
Fibrin clot dynamics
 Lag time (s)− 23.61 (− 56.2 to 8.98)0.23718.28 (− 8.57 to 45.12)0.29541.8 (7.41 to 76.37)0.012
  1. AA arachidonic acid