Sodium–glucose cotransporter 2 inhibitor Dapagliflozin attenuates diabetic cardiomyopathy

Table 1 Body and heart weight and biochemical markers

Groups/mice	Wt/wt	Wt/wt + ATII	Db/db	Db/db + DAPA	Db/db + ATII	Db/db + ATII + DAPA
Numbers	8	6	5	4	8	5
Body weight (g)	25.5 ± 1	25.5 ± 1.5	41.5 ± 5⁺	42.8 ± 2⁺	38.8 ± 8⁺	45.3 ± 5⁺
Blood pressure (mmHg)	95 ± 5	137 ± 5⁺	102 ± 3	97 ± 3	147 ± 3^+,*	133 ± 2^+,*^,#
Blood glucose (mg/dl)	298 ± 55	258 ± 76	937 ± 75⁺	607 ± 30^+,*	874 ± 111⁺	556 ± 57^+,&
Blood cholesterol	118 ± 25	143 ± 5	120 ± 10	143 ± 22	202 ± 77	188 ± 35

⁺p < 0.05 vs wt/wt, *p < 0.05 vs db/db, ^&p < 0.05 vs db/db + ATII, ^#p < 0.002 vs db/db + ATII

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