Skip to main content

Table 3 Hazard ratios (HRs) of peripheral vascular disease based on HbA1c and FPG-CV levels in persons with diabetes enrolled in the National Diabetes Care Management Program, Taiwan (n = 30,932)

From: Fasting plasma glucose variability and HbA1c are associated with peripheral artery disease risk in type 2 diabetes

VariablesnCasesPerson-yearsIRPeripheral vascular disease (N = 894)
Age and gender-adjustedMultivariate-adjustedaMultivariate-adjustedb
HbA1c (%)
 < 626635921,708.262.721.001.001.00
 6–813,535377111,972.543.372.31 (1.72, 3.11)***1.20 (0.90, 1.58)1.19 (0.90, 1.57)
 8–10922924775,713.953.262.29 (1.69, 3.10)***1.06 (0.79, 1.42)1.05 (0.78, 1.41)
 ≥ 10550521144,117.074.783.52 (2.59, 4.76)***1.52 (1.12, 2.06)**1.50 (1.10, 2.04)**
p for trend    < 0.0010.010.01
FPG-CV (%)
 ≤ 17.510,21425185,777.392.931.001.001.00
 17.5–34.810,19930684,671.993.611.34 (1.13, 1.59)***1.18 (1.00, 1.40)1.17 (0.99, 1.39)
 > 34.810,51933783,062.434.061.44 (1.21, 1.71)***1.25 (1.05, 1.48)*1.24 (1.04, 1.47)*
p for trend    < 0.0010.010.01
  1. Multivariate-adjusteda for age, gender, alcohol consumption, smoking, diabetes duration, type of hypoglycemic medication, hypertension medication and obesity
  2. Multivariate-adjustedb for cardiovascular risk factors, stroke, coronary artery disease, cancer, congestive heart failure, hyperlipidemia, atrial fibrillation, hypertension, chronic hepatitis, hypoglycemia and chronic obstructive pulmonary disease in addition to the variables in first multivariate model
  3. IR incidence density rate = number of incident cases/person-years * 1000
  4. * p < 0.05; ** p < 0.01; *** p < 0.001