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Table 1 Baseline characteristics of patients

From: Association of glycemic variability with left ventricular diastolic function in type 2 diabetes mellitus

Variables

All patients (n = 100)

Clinical characteristics

 Age, years

60 ± 14

 Gender (female), n (%)

45 (45)

 DM duration, years

10 (0.1–42)

 Body weight, kg

67 ± 16

 BSA, m2

1.70 ± 0.22

 Systolic blood pressure, mmHg

129 ± 19

 Heart rate, bpm

74 ± 10

 BUN, mg/dL

15.6 ± 5.7

 Creatinine, mg/dL

0.86 ± 0.43

 eGFR, mL/min/1.73 m2

73.4 ± 25.4

 HbA1c, %

8.5 ± 1.9

Comorbidities, n (%)

 Hypertension

58 (58)

 Dyslipidemia

63 (63)

Anti-hypertensive drugs, n (%)

 Calcium channel blockers

38 (38)

 ACE inhibitor/ARB

54 (54)

 Mineralocorticoid receptor antagonist

1 (1)

Anti-diabetic drugs, n (%)

 DPP-4 inhibitor

51 (51)

 GLP-1 RA

11 (11)

 SU

28 (28)

 α-GI

23 (23)

 Thiazalidine

8 (8)

 Metformin

57 (57)

 SGLT2 inhibitor

3 (3)

Echocardiographic parameters

 LV end-diastolic volume, mL

76.0 ± 22.0

 LV end-systolic volume, mL

26.8 ± 10.7

 LVEF, %

65.6 ± 4.9

 LVMI, g/m2

80.0 ± 19.0

 LAVI, mL/m2

30.1 ± 8.0

 e’, cm/s

6.05 ± 1.67

 E/e’

10.5 ± 3.4

Trans-mitral flow

 E, cm/s

59.4 ± 13.7

 DcT, msec

207 ± 53

 E/A

0.8 ± 0.2

Pulmonary venous flow

 S, cm/s

65.4 ± 16.1

 D, cm/s

41.3 ± 8.0

 S/D

1.6 ± 0.4

 A, cm/s

38.2 ± 20.0

  1. Values are mean ± SD for normally distributed data and median and interquartile range for non-normally distributed data, or n (%). Assessment of pulmonary venous flow was available in 90 patients
  2. DM diabetes mellitus, BSA body surface area, BUN blood urea nitrogen, eGFR estimated glomerular filtration rate, ACE angiotensin-converting enzyme, ARB angiotensin II receptor blocker, DPP-4 Dipeptidyl Peptidase-4, GLP-1 RA glucagon-like peptide-1 receptors agonists, SU Sulfonylureas, α-GI α-glucosidase inhibitors, SGLT2 Sodium glucose cotransporter type 2, LVEF left ventricular ejection fraction, LVMI left ventricular mass index, LAVI left atrial volume index, e’ spectral pulsed-wave Doppler-derived early diastolic velocity from the septal mitral annulus, E peak early diastolic mitral flow velocity, DcT E wave deceleration time, E/A peak early and late diastolic mitral flow velocity ratio, S peak systolic velocity of pulmonary venous flow, D peak diastolic velocity of pulmonary venous flow, A peak velocity of pulmonary venous flow during atrial systole