Variable | Pitavastatin 1 mg (n = 251) | Pitavastatin 4 mg (n = 251) | p-value |
---|---|---|---|
Age (years) | 63.3 ± 12.2 | 62.6 ± 11.9 | 0.54 |
Male sex | 177 (70.5%) | 185 (73.7%) | 0.49 |
Body mass index (kg/m2) | 24.4 ± 3.0 | 24.6 ± 3.0 | 0.66 |
Diagnosis | 0.88 | ||
Unstable angina | 184 (73.3%) | 181 (72.1%) | |
Non-ST elevation MI | 37 (14.7%) | 41 (16.3%) | |
ST elevation MI | 30 (12.0%) | 29 (11.6%) | |
Risk factors | |||
Hypertension | 142 (56.6%) | 144 (57.4%) | 0.93 |
Smoking status | 0.94 | ||
Current smoker | 64 (25.5%) | 65 (25.9%) | |
Ex-smoker | 46 (18.3%) | 43 (17.1%) | |
Never smoker | 141 (56.2%) | 143 (57.0%) | |
Alcoholics | 46 (18.3%) | 44 (17.5%) | 0.91 |
Prior stroke | 0 (0.0%) | 0 (0.0%) | – |
Medication on admission | |||
Aspirin | 251 (100.0%) | 251 (100.0%) | – |
Clopidogrel | 215 (85.7%) | 204 (81.3%) | 0.23 |
Ticagrelor | 40 (15.9%) | 48 (19.1%) | 0.41 |
Prasugrel | 10 (4.0%) | 20 (8.0%) | 0.09 |
ACE inhibitor | 41 (16.3%) | 49 (19.5%) | 0.42 |
ARB | 82 (32.7%) | 78 (31.1%) | 0.77 |
β-blocker | 117 (46.6%) | 118 (47.0%) | 0.99 |
CCB | 86 (34.3%) | 84 (33.5%) | 0.93 |
Diuretics | 49 (19.5%) | 44 (17.5%) | 0.65 |
Laboratory findings | |||
Total cholesterol (mg/dL) | 177.9 ± 41.4 | 180.8 ± 46.6 | 0.46 |
Triglyceride (mg/dL) | 145.7 ± 109.7 | 162.6 ± 182.6 | 0.21 |
HDL cholesterol (mg/dL) | 43.4 ± 10.6 | 42.9 ± 9.9 | 0.60 |
LDL cholesterol (mg/dL) | 122.9 ± 34.2 | 123.4 ± 34.2 | 0.88 |
Creatinine (mg/dL) | 1.1 ± 1.5 | 0.9 ± 0.2 | 0.08 |
Uric acid (mg/dL) | 5.6 ± 1.5 | 5.8 ± 1.6 | 0.23 |
hsCRP (mg/L) | 5.6 ± 11.8 | 6.7 ± 15.9 | 0.43 |
Fasting glucose (mmol/L) | 115.4 ± 29.3 | 114.9 ± 26.3 | 0.85 |
HbA1c (%) | 5.8 ± 0.4 | 5.8 ± 0.3 | 0.36 |