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Fig. 1 | Cardiovascular Diabetology

Fig. 1

From: Microvascular complications burden (nephropathy, retinopathy and peripheral polyneuropathy) affects risk of major vascular events and all-cause mortality in type 1 diabetes: a 10-year follow-up study

Fig. 1

Kaplan–Meier curves for all-cause death and cumulative incidences of major vascular and coronary events by MC. no-MC: dotted green line, 1 MC: dashed blue line, 2 MC: dashdotted violet line, 3 MC: solid red line. Percentages of events and Cox proportional unadjusted HRs (95% CI) are shown for each MC group. a Survival from all-cause death: K–M Logrank 187.35, p < 0.0001. Pairwise over strata logrank statistic provides the following results: 1 MC vs. no-MC, logrank 10.96 (p = 0.0009); 2 MC vs. no-MC, logrank 22.77 (p < 0.0001); furthermore, 3 MC vs. no-MC, logrank 223.18, vs. 1 MC, logrank 78.94 and vs. 2 MC, logrank 30.62 (p < 0.0001, for all). b Cumulative incidence of major vascular events: K–M Logrank 127.61, p < 0.0001. Pairwise over strata logrank statistic provides the following results: 1 MC vs. no-MC, logrank 3.71 (p = 0.054); 2 MC vs. no-MC, logrank 67.22 and vs. 1 MC, logrank 28.49 (p < 0.0001, for both); furthermore, 3 MC vs. no-MC, logrank 110.38, vs. 1 MC, logrank 57.81 (p < 0.0001, for both) and vs. 2 MC, logrank 4.15 (p = 0.042). c Cumulative incidence of coronary events: K–M Logrank 81.47, p < 0.0001. Pairwise over strata logrank statistic provides the following results: 2 MC vs. no-MC, logrank 40.60 and vs. 1 MC, logrank 26.17 (p < 0.0001, for both); 3 MC vs. no-MC, logrank 55.23, vs. 1 MC, logrank 44.18 (p < 0.0001, for both)

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