Table 2 Predictors of time to first hHF (SMQ definition)
Baseline predictor | Hazard ratio [95% CI] | Relative importance | P-value |
|---|---|---|---|
Prior heart failure (Y vs. N) | 4.89 [3.90; 6.14] | 54.6 | < 0.0001 |
Hepatic impairment (Y vs. N) | 3.08 [2.15; 4.41] | 11.0 | < 0.0001 |
eGFR (log regression) | 0.44 [0.34; 0.58] | 10.0 | < 0.0001 |
Atrial fibrillation (Y vs. N) | 1.95 [1.50; 2.55] | 7.2 | < 0.0001 |
Total insulin dose (U/kg) at week 1 | 1.53 [1.27; 1.84] | 5.9 | < 0.0001 |
Prior myocardial infarction (Y vs. N) | 1.54 [1.23; 1.91] | 4.3 | 0.0001 |
Macular edema (Y vs. N) | 3.77 [1.40; 10.2] | 2.0 | 0.0087 |
A1C (squared regression) | 1.00 [1.00; 1.01] | 1.8 | 0.0137 |
Proteinuria (microalbuminuria and gross proteinuria) | 1.36 [1.06; 1.73] | 1.8 | 0.0140 |
Systolic blood pressure at baseline | 1.01 [1.00; 1.01] | 1.5 | 0.0251 |