Q1 | Q2 | Q3 | Q4 | p linear trend | 1 SD increase | 1 SD increase (adjusted for 1-year changes in 2-AAA and pipecolic acid) | |
---|---|---|---|---|---|---|---|
1-year change lysine | |||||||
Outcome: T2D | |||||||
MV adjusted modelb | Ref. | 0.72 (0.37–1.40) | 0.43 (0.17–1.07) | 0.62 (0.29–1.34) | 0.215 | 0.88 (0.65–1.20) | 0.80 (0.58–1.10) |
Outcome: CVD | |||||||
MV adjusted modela | Ref. | 1.07 (0.63–1.82) | 0.93 (0.52–1.66) | 0.93 (0.52–1.64) | 0.796 | 0.95 (0.77–1.18) | 0.99 (0.80–1.24) |
Q1 | Q2 | Q3 | Q4 | p linear trend | 1 SD increase | 1 SD increase (adjusted for 1-year changes in lysine and pipecolic acid) | |
---|---|---|---|---|---|---|---|
1-year change 2-AAA | |||||||
Outcome: T2D | |||||||
MV adjusted modelb | Ref. | 1.30 (0.63–2.67) | 0.95(0.38–2.36) | 1.66 (0.82–3.39) | 0.214 | 1.23 (0–96–1.58) | 1.29 (0.98–1.70) |
Outcome: CVD | |||||||
MV adjusted modela | Ref. | 0.94 (0.52–1.69) | 0.97 (0.55–1.72) | 0.66 (0.35–1.21) | 0.210 | 0.84 (0.67–1.05) | 0.81 (0.63–1.04) |
Q1 | Q2 | Q3 | Q4 | p linear trend | 1 SD increase | 1 SD increase (adjusted for 1-year changes in lysine and 2-AAA) | |
---|---|---|---|---|---|---|---|
1-year change pipecolic acid | |||||||
Outcome: T2D | |||||||
MV adjusted modelb | Ref. | 1.45 (0.54–3.84) | 1.22 (0.43–3.46) | 1.42 (0.54–3.71) | 0.483 | 1.08 (0.81–1.44) | 1.18 (0.88–1.58) |
Outcome: CVD | |||||||
MV adjusted modela | Ref. | 0.49 (0.21–1.12) | 0.52 (0.24–1.13) | 0.93 (0.47–1.84) | 0.593 | 1.03 (0.83–1.28) | 1.10 (0.87–1.37) |