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Table 3 Univariate and multivariate analysis and predictors of MACCEs within 1 year after PCI

From: High triglyceride–glucose index is associated with poor prognosis in patients with acute ST-elevation myocardial infarction after percutaneous coronary intervention

VariableUnivariate analysisMultivariate analysis
OR95% CIP valueOR95% CIP value
TyG index grouping
 Q11  1  
 Q21.0960.778–1.5450.6001.1170.668–1.8430.587
 Q31.5421.083–2.1940.0161.3560.852–2.1600.199
 Q41.8091.263–2.5900.0011.5291.001–2.0610.003
Age, years1.0211.011–1.032< 0.0011.0110.992–1.0310.233
Male0.9220.676–1.2560.605   
BMI, kg/m21.0050.950–1.0430.460   
SBP, mmHg1.0010.994–1.0060.839   
DBP, mmHg0.9900.981–0.9990.0290.9930.982–1.0050.258
Heart rate, bpm0.9990.991–1.0080.905   
Killip class > 12.1881.667–2.874< 0.0011.7221.185–2.4710.002
Smoker1.3471.047–1.7330.0201.1910.858–1.6530.297
Hypertension1.6311.250–2.127< 0.001   
Diabetes mellitus1.6721.261–2.216< 0.001   
Anemia1.3510.940–1.941< 0.0011.2820.995–1.5630.024
Previous AMI1.1510.499–2.6550.742   
Atrial fibrillation0.8640.463–1.6110.645   
Biochemical indicators
 NT-proBNP, pg/mL (IQR)1.0570.909–1.1580.770   
 Cardiac troponin I, ng/ml1.0180.830–1.2570.571   
 hs-CRP, mg/L (IQR)1.0260.975–1.0740.302   
 White blood cells, 109/L1.0371.001–1.0750.0471.0380.988–1.0910.141
 Neutrophil ratio0.9980.988–1.0080.680   
 Platelet, 109/L1.0021.000–1.0040.0251.0020.999–1.0040.285
 Albumin, g/L0.9710.947–0.9960.0230.9630.928–1.0000.050
 Measured HbA1c,  %1.1731.042–1.3210.005   
 FPG, mmol/L1.0401.010–1.0720.009   
 TC, mmol/L1.0150.916–1.1240.781   
 Triglycerides, mmol/L1.0210.909–1.1310.503   
 HDL-C, mmol/L0.8130.494–1.3390.813   
 LDL-C, mmol/L0.9380.806–1.0920.412   
 Uric acid, umol/L1.0021.001–1.0030.0021.0021.000–1.0040.013
 eGFR, mL/min0.9950.991–0.9990.0090.9990.993–1.0050.751
Coronary angiography
 GPIIb/IIIa antagonists0.9100.703–1.1760.470   
 Anticoagulation1.4060.773–2.5570.264   
 Lesion vessels1.1631.071–1.263< 0.0011.0920.960–1.2430.180
 Three-vessel disease1.3941.084–1.7930.0101.2440.830–1.8650.289
 Number of stents1.5751.220–2.032< 0.0011.7091.229–2.3750.001
 Gensini score1.0081.002–1.0170.0221.0020.993–1.0100.366
 LVEF0.3030.099–0.9310.0370.1210.029–0.0570.004
Medications use at discharge
 Aspirin0.6870.368–1.2820.238   
 Clopidogrel/ticagrelor0.7820.276–2.2130.643   
 Statin1.7760.834–3.7810.136   
 Beta blockers0.9790.716–1.3390.895   
 ACEI/ARB1.2080.917–1.5900.179   
  1. Co-linearity analysis showed that hypertension, diabetes, HbA1c, FPG and TyG index had high co-linearity. Therefore, hypertension, diabetes, HbA1c and FPG weren’t included in multivariate model
  2. BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, AMI acute myocardial infarction, IQR interquartile range, hs-CRP hypersensitive C-reactive protein, TC total cholesterol, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, SCr Serum creatinine concentration, eGFR estimated glomerular filtration rate, LVEF left ventricular ejection fraction, ACEI angiotensin converting enzyme inhibitor, ARB angiotensin receptor blocker