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Table 7 Multivariable models predicting FMDmm using Δψm, prohibitin, and UCP2 with clinical variables in healthy control subjects

From: Circulating levels of mitochondrial uncoupling protein 2, but not prohibitin, are lower in humans with type 2 diabetes and correlate with brachial artery flow-mediated dilation

 ΔψmProhibitinUCP2
AgeΒ = − 0.0002, P = 0.76Β = − 0.0005, P = 0.65Β = − 0.0004, P = 0.69
SexΒ = 0.049, P < 0.001Β = 0.047, P < 0.001Β = 0.048, P < 0.001
SBP ≥ 130 mmHgΒ = 0.015, P = 0.33Β = 0.016, P = 0.28Β = 0.017, P = 0.35
BMI ≥ 30 kg/m2Β = 0.011, P = 0.33Β = 0.008, P = 0.55Β = 0.011, P = 0.35
Fasting blood glucoseΒ = 0.002, P = 0.001Β = 0.002, P = 0.001Β = 0.002, P = 0.001
Plasma LDL cholesterolΒ = − 0.0003, P = 0.11Β < 0.001, P = 0.15Β = − 0.0002, P = 0.13
Mitochondrial biomarkerΒ = 0.00003, P = 0.95Β = 0.001, P = 0.58Β = − 0.001, P = 0.82
  1. Italic values indicate p < 0.05
  2. BMI body mass index, SBP systolic blood pressure