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Fig. 4 | Cardiovascular Diabetology

Fig. 4

From: Liraglutide improves lipid metabolism by enhancing cholesterol efflux associated with ABCA1 and ERK1/2 pathway

Fig. 4

Effects of liraglutide on RCT and RCT-related protein expression in mice study. Liraglutide treatment increased the efflux of 3H-cholesterol from macrophages to plasma and feces in db/db mice with HFD (a), enhanced hepatic ABCA1 expression, and unchanged ABCG1 and SR-B1 expressions in mice (b). ****p < 0.0001: db/db + HFD vs db/db + ND or WT + ND ##p < 0.01: db/db + HFD + LIRA vs db/db + HFD. &&&p < 0.001: db/db + HFD + AT vs db/db + HFD

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