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Table 3 Angiography imaging results relative to PCSK9 groups

From: Association of PCSK9 plasma levels with metabolic patterns and coronary atherosclerosis in patients with stable angina

 

CTA population (n = 412)

Quartile I

< 136 ng/L

n = 103

Quartile II–III

136–266 ng/L

n = 206

Quartile IV

> 266 ng/L

n = 103

P value

Obstructive CAD at CTA

 Stenosis > 50%

144 (35)

40 (39)

71 (34)

33 (32)

ns

 Stenosis > 70%

45 (11)

12 (12)

23 (11)

10 (10)

ns

Coronary plaques

 Total N. of plaques

3.9 ± 3.8

4.36 ± 3.89

3.67 ± 3.77

3.37 ± 3.77

0.0621*

 N. of non-obstructive plaques

3.0 ± 3.1

3.33 ± 2.89

3.14 ± 3.10

2.42 ± 2.93

0.0322*

 N. of obstructive plaques

0.9 ± 1.7

0.94 ± 1.57

0.73 ± 1.42

0.85 ± 1.87

ns

 N. of calcified plaques

0.9 ± 1.7

0.85 ± 1.84

0.93 ± 1.69

0.81 ± 1.74

ns

 N. of mixed plaques

2.6 ± 3.2

3.14 ± 3.42

2.49 ± 3.12

2.19 ± 3.15

0.0356*

 N. of non-calcified plaques

0.5 ± 0.9

0.38 ± 0.85

0.54 ± 1.02

0.38 ± 0.72

ns

CTA score

12 ± 11

13.17 ± 11.53

11.83 ± 10.71

9.99 ± 11.11

0.0391*

  1. Continuous variables are presented as mean ± standard deviation, categorical variables as absolute N and (%)
  2. * I vs. IV quartile