Table 3 Risk of myocardial infarction and stroke in patients with type 2 diabetes mellitus according to non-high-density lipoprotein cholesterol (non-HDL-C) category
| Â | Total | Statin non-user | Statin user | ||||||
|---|---|---|---|---|---|---|---|---|---|
Events (n) | Incidence rate (per 1000 person-years) | HR (95% CI)* | Events (n) | Incidence rate (per 1000 person-years) | HR (95% CI)* | Events (n) | Incidence rate (per 1000 person-years) | HR (95% CI)* | |
Myocardial infarction | |||||||||
 < 100 | 5609 | 3.37 | 1 (ref.) | 2521 | 3.38 | 1 (ref.) | 3088 | 3.36 | 1 (ref.) |
 100–129 | 11,540 | 3.35 | 1.07 (1.03, 1.10) | 6898 | 3.13 | 0.97 (0.92, 1.0) | 4642 | 3.76 | 1.16 (1.11, 1.21) |
 130–159 | 14,768 | 3.51 | 1.19 (1.15, 1.23) | 10,638 | 3.30 | 1.07 (1.02, 1.12) | 4130 | 4.18 | 1.33 (1.27, 1.40) |
 160–189 | 11,614 | 3.87 | 1.38 (1.34, 1.43) | 8248 | 3.66 | 1.26 (1.20, 1.31) | 3366 | 4.49 | 1.49 (1.42, 1.57) |
 ≥ 190 | 9158 | 4.57 | 1.69 (1.63, 1.75) | 5607 | 4.50 | 1.64 (1.57, 1.72) | 3551 | 4.68 | 1.63 (1.55, 1.71) |
P for trend |  |  | < 0.0001 |  |  | < 0.0001 |  |  | < 0.0001 |
Stroke | |||||||||
 < 100 | 9171 | 5.55 | 1 (ref.) | 4514 | 6.10 | 1 (ref.) | 4657 | 5.10 | 1 (ref.) |
 100–129 | 18,768 | 5.49 | 1.05 (1.02, 1.07) | 12,045 | 5.50 | 0.96 (0.92, 0.99) | 6723 | 5.47 | 1.13 (1.08, 1.17) |
 130–159 | 23,725 | 5.68 | 1.15 (1.12, 1.17) | 17,766 | 5.56 | 1.03 (0.99, 1.06) | 5959 | 6.07 | 1.30 (1.25, 1.35) |
 160–189 | 17,435 | 5.85 | 1.25 (1.22, 1.29) | 12,748 | 5.70 | 1.12 (1.08, 1.16) | 4687 | 6.30 | 1.42 (1.36, 1.48) |
 ≥ 190 | 12,194 | 6.11 | 1.39 (1.35, 1.43) | 7563 | 6.10 | 1.29 (1.24, 1.34) | 4631 | 6.14 | 1.45 (1.39, 1.52) |
P for trend |  |  | < 0.0001 |  |  | < 0.0001 |  |  | < 0.0001 |