| Total | Statin non-user | Statin user | ||||||
---|---|---|---|---|---|---|---|---|---|
Events (n) | Incidence rate (per 1000 person-years) | HR (95% CI)* | Events (n) | Incidence rate (per 1000 person-years) | HR (95% CI)* | Events (n) | Incidence rate (per 1000 person-years) | HR (95% CI)* | |
Myocardial infarction | |||||||||
 < 70 | 5342 | 3.50 | 1 (ref.) | 2330 | 3.44 | 1 (ref.) | 3012 | 3.55 | 1 (ref.) |
 70–99 | 12,274 | 3.41 | 1.02 (0.99, 1.06) | 7152 | 3.22 | 0.95 (0.91, 1.00) | 5122 | 3.71 | 1.07 (1.03, 1.12) |
 100–129 | 15,366 | 3.52 | 1.12 (1.09, 1.16) | 11,122 | 3.31 | 1.02 (0.97, 1.07) | 4244 | 4.22 | 1.26 (1.20, 1.32) |
 130–159 | 10,981 | 3.88 | 1.29 (1.25, 1.34) | 7985 | 3.69 | 1.19 (1.14, 1.25) | 2996 | 4.51 | 1.39 (1.32, 1.46) |
 ≥ 160 | 6828 | 4.56 | 1.56 (1.51, 1.62) | 4228 | 4.53 | 1.53 (1.46, 1.62) | 2600 | 4.60 | 1.49 (1.41, 1.57) |
 P for trend |  |  | < 0.0001 |  |  | < 0.0001 |  |  | < 0.0001 |
Stroke | |||||||||
 < 70 | 8527 | 5.63 | 1 (ref.) | 4077 | 6.07 | 1 (ref.) | 4450 | 5.27 | 1 (ref.) |
 70–99 | 19,873 | 5.56 | 1.03 (1.00, 1.05) | 12,387 | 5.62 | 0.96 (0.93, 1.00) | 7486 | 5.46 | 1.07 (1.03, 1.11) |
 100–129 | 24,759 | 5.72 | 1.11 (1.08, 1.14) | 18,611 | 5.59 | 1.01 (0.97, 1.04) | 6148 | 6.16 | 1.25 (1.20, 1.30) |
 130–159 | 16,354 | 5.82 | 1.19 (1.15, 1.22) | 12,211 | 5.68 | 1.08 (1.04, 1.12) | 4143 | 6.27 | 1.31 (1.26, 1.37) |
 ≥ 160 | 9047 | 6.07 | 1.30 (1.26, 1.34) | 5655 | 6.09 | 1.21 (1.17, 1.26) | 3392 | 6.04 | 1.33 (1.27, 1.40) |
 P for trend |  |  | < 0.0001 |  |  | < 0.0001 |  |  | < 0.0001 |