Table 4 Association between T2D and cardiovascular parameters
From: Phenotyping diabetic cardiomyopathy in Europeans and South Asians
| Â | Adjusted mean difference (95% CI) between T2D patients and controls | P value for interaction by ethnicity | |
|---|---|---|---|
Europeans (n = 77) | South Asians (n = 54) | ||
LV diastolic function | |||
 E/A | − 0.20 (− 0.36, − 0.04) | − 0.20 (− 0.36, − 0.03) | 0.480 |
 E dec peak, mL/s2 ×10−3 | 0.35 (− 0.13, 0.83) | − 0.03 (− 0.54, 0.49) | 0.576 |
 Ea, cm/s | − 1.1 (− 1.9, − 0.4) | − 0.4 (− 1.4, 0.6) | 0.095 |
 LV filling pressure, mmHg | 2.3 (1.0, 3.6) | 1.0 (− 0.4, 2.4) | 0.300 |
 LV compliance, mL/mmHg | − 12.9 (− 18.6, − 7.2) | − 1.5 (− 6.1, 3.1) | 0.008 |
LV systolic function | |||
 GLS, % | 0.6 (− 0.9, 2.1) | 1.3 (− 0.2, 2.8) | 0.708 |
Hemodynamics | |||
 Stroke volume, mL | − 10 (− 19, − 1) | 3 (− 4, 11) | 0.007 |
 Cardiac output, L/min | 0.3 (− 0.3, 0.8) | 0.8 (0.3, 1.3) | 0.067 |
 Cardiac index, L/min/m2 | − 0.2 (− 0.4, 0.0) | 0.1 (− 0.1, 0.3) | 0.012 |
Aortic stiffness | |||
 Aortic pulse wave velocity, m/s | 0.2 (− 0.8, 1.2) | 0.6 (− 0.2, 1.4) | 0.761 |
LV structure | |||
 End-diastolic volume, mL | − 20 (− 34, − 7) | 11 (0, 22) | 0.001 |
 Mass, g | − 1 (− 11, 8) | 22 (15, 30) | 0.005 |
 Concentricity, g/mL | 0.10 (0.04, 0.15) | 0.14 (0.07, 0.21) | 0.574 |
Myocardial tissue characteristics | |||
 Myocardial Tg content, % | 0.59 (0.35, 0.84) | 0.10 (− 0.20, 0.41) | 0.002 |
 Native T1, ms | − 25 (− 47, − 3) | − 6 (− 31, 18) | 0.078 |
 Extracellular volume fraction, % | 1.0 (− 0.3, 2.2) | − 1.9 (− 3.4, − 0.4) | 0.114 |
 Extracellular volume, mL | − 1 (− 2, 4) | 4 (2, 7) | 0.071 |
 Cell volume, mL | − 3 (− 10, 4) | 17 (12, 23) | 0.003 |