Impact of free fatty acids on prognosis in coronary artery disease patients under different glucose metabolism status

Table 2 Relation of the continuous plasma FFAs levels and cardiovascular risk factors with MACEs

Variables	Univariate Cox regression		Multivariate Cox regression
Variables	HR (95% CI)	p-value	HR (95% CI)	p-value
Age	1.024 (1.016–1.032)	< 0.001	1.020 (1.010–1.029)	< 0.001
Sex	1.015 (0.849–1.213)	0.870	–
BMI	0.990 (0.965–1.016)	0.457	–
LVEF	0.975 (0.962–0.987)	< 0.001	0.979 (0.971–0.988)	< 0.001
Hypertension	1.320 (1.111–1.586)	0.002	1.221 (1.017–1.466)	0.032
DM status	1.352 (1.201–1.522)	0.020	1.200 (1.060–1.359)	0.004
Smoke	1.005 (0.857–1.179)	0.951	–
FH	1.240 (0.973–1.582)	0.082
Log transformed TG	1.038 (1.980–1.100)	0.205	–	–
HDL-C	1.142 (0.856–1.522)	0.376	–
LDL-C	1.014 (0.937–1.097)	0.730	–
GS	1.007 (1.005–1.009)	< 0.001	1.005 (1.003–1.007)	< 0.001
Log₂FFAs	1.361 (1.191–1.554)	< 0.001	1.242 (1.084–1.424)	0.002
Baseline Statin	0.817 (0.697–0.959)	0.013	0.792 (0.671–0.936)	0.006

Univariate and multivariate Cox proportional hazards regression analysis was performed to test statistical significance
MACEs were cardiovascular mortality, non-fatal myocardial infarction (MI), stroke and post-discharge unplanned revascularization
MACEs major cardiovascular adverse events, BMI body mass index, TG triglyceride, LDL-C low density lipoprotein cholesterol, HDL-C high density lipoprotein cholesterol, FFAs free fatty acids, LVEF left ventricular ejection fraction, DM diabetes mellitus, FH family history of coronary artery disease, GS gensini score

ISSN: 1475-2840