Biomarker | Week of pregnancy | Sensitivity (%) | Specificity (%) | References |
---|---|---|---|---|
SHGB | 1st–12th | 85.0 | 55.3 | |
hs-CRP | 4–6th | 89.0 | 55.3 | [121] |
11–14th | 86.2 | 50.8 | [122] | |
FGF-21 | 24–28th | 100.0 | 75.0 | [148] |
miR-16-5p | 4–6th | 41.6 | 95.8 | [159] |
miR-17-5p | 4–6th | 21.4 | 95.4 | |
miR-20a-5p | 4–6th | 17.8 | 95.4 | |
FABP4 | 4–6th | 81.8 | 71.2 | [133] |
23rd–30th | 87.0 | 89.0 | [135] | |
Adiponectin | 16–18th | 80.7 | 65.1 | [117] |
24–28th | 83.6 | 56.6 | [113] | |
RBP4 | 16–18th | 79.4 | 79.1 | [136] |
63.6 | 75.0 | [117] | ||
Leptin | 24–28th | 81.2 | 64.2 | [113] |
miR-132 | 16th | 66.7 | 63.3 | [154] |
miR-29a | ||||
miR-222 | ||||
Ficolin-3 | 16–18th | 51.1 | 97.7 | [117] |
Fetuin-A | 11–14th | 58.6 | 76.2 | [122] |
miR-21-3p | 30–36th | 52.6 | 89.3 | [165] |