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Table 2 Impact of body weight status and diabetes on new-onset atrial fibrillation

From: The impact of body weight and diabetes on new-onset atrial fibrillation: a nationwide population based study

  n Event Patient*years Incidence Model 1 (95% CI) Model 2 (95% CI) Model 3 (95% CI)
Total
 BMI
  < 18.5 374,501 5565 3,019,377 1.843 1.020 (0.993–1.049) 1.055 (1.026–1.085) 1.053 (1.025–1.083)
  18.5–23 3,867,084 62,946 31,641,170 1.989 1 (reference) 1 (reference) 1 (reference)
  23–25 2,423,219 50,163 19,850,785 2.527 1.125 (1.112–1.138) 1.040 (1.028–1.052) 1.042 (1.030–1.055)
  25–30 2,795,090 68,242 22,864,770 2.985 1.290 (1.276–1.304) 1.123 (1.111–1.136) 1.128 (1.115–1.140)
  30– 337,524 9220 2,754,059 3.348 1.606 (1.572–1.642) 1.327 (1.298–1.357) 1.325 (1.296–1.354)
 WC (M/F)
  < 80/75 3,621,432 44,263 29,751,411 1.488 0.726 (0.717–0.736) 0.829 (0.818–0.840) 0.836 (0.825–0.848)
  − 85/80 2,327,214 43,245 19,058,845 2.269 0.870 (0.859–0.882) 0.921 (0.909–0.934) 0.927 (0.915–0.939)
  − 90/85 1,936,668 46,009 15,812,732 2.910 1 (reference) 1 (reference) 1 (reference)
  − 95/90 1,134,028 33,661 9,219,448 3.651 1.148 (1.132–1.164) 1.096 (1.080–1.111) 1.092 (1.076–1.107)
  − 100/95 504,432 17,713 4,085,267 4.336 1.252 (1.230–1.274) 1.176 (1.155–1.196) 1.162 (1.142–1.183)
  ≥ 100/95 273,644 11,245 2,202,458 5.106 1.615 (1.582–1.649) 1.410 (1.381–1.440) 1.369 (1.341–1.398)
Non-diabetic + IFG
 BMI
  < 18.5 361,941 5055 2,931,149 1.725 1.034 (1.004–1.064) 1.056 (1.025–1.087) 1.058 (1.028–1.089)
  18.5–23 3,653,082 54,833 29,975,508 1.829 1 (reference) 1 (reference) 1 (reference)
  23–25 2,206,558 41,998 18,127,691 2.317 1.129 (1.114–1.143) 1.050 (1.036–1.063) 1.049 (1.036–1.062)
  25–30 2,453,625 54,545 20,131,059 2.709 1.288 (1.273–1.303) 1.134 (1.120–1.148) 1.133 (1.119–1.147)
  30– 279,364 6663 2,287,495 2.913 1.541 (1.502–1.581) 1.309 (1.275–1.343) 1.294 (1.261–1.327)
 WC (M/F)
  < 80/75 3,490,482 40,229 28,724,841 1.401 0.727 (0.717–0.737) 0.820 (0.808–0.832) 0.833 (0.821–0.845)
  − 85/80 2,148,892 37,280 17,642,987 2.113 0.872 (0.859–0.884) 0.918 (0.905–0.931) 0.926 (0.913–0.940)
  − 90/85 1,722,709 37,924 14,109,867 2.688 1 (reference) 1 (reference) 1 (reference)
  − 95/90 968,520 26,661 7,904,775 3.373 1.154 (1.136–1.172) 1.107 (1.089–1.124) 1.101 (1.083–1.118)
  − 100/95 412,804 13,266 3,359,409 3.949 1.244 (1.219–1.269) 1.185 (1.161–1.208) 1.163 (1.140–1.186)
  ≥ 100/95 211,163 7734 1,711,022 4.520 1.594 (1.556 –1.634) 1.418 (1.384–1.454) 1.365 (1.332–1.399)
Diabetic
 BMI
  < 18.5 12,560 510 88,228 5.780 1.096 (1.002–1.198) 1.119 (1.024–1.224) 1.100 (1.006–1.203)
  18.5–23 214,002 8113 1,665,662 4.871 1 (reference) 1 (reference) 1 (reference)
  23–25 216,661 8165 1,723,094 4.739 0.993 (0.963–1.024) 0.970 (0.940–1.000) 0.972 (0.942–1.002)
  25–30 341,465 13,697 2,733,711 5.010 1.104 (1.074–1.134) 1.053 (1.024–1.082) 1.054 (1.025–1.084)
  30– 58,160 2557 466,564 5.480 1.486 (1.421–1.554) 1.362 (1.301–1.425) 1.341 (1.282–1.403)
 WC (M/F)
  < 80/75 130,950 4034 1,026,570 3.930 0.920 (0.886–0.955) 0.963 (0.927–1.001) 0.965 (0.929–1.003)
  − 85/80 178,322 5965 1,415,858 4.213 0.925 (0.895–0.957) 0.945 (0.914–0.977) 0.949 (0.917–0.981)
  − 90/85 213,959 8085 1,702,865 4.748 1 (reference) 1 (reference) 1 (reference)
  − 95/90 165,508 7000 1,314,673 5.325 1.084 (1.050–1.119) 1.062 (1.029–1.097) 1.054 (1.021–1.089)
  − 100/95 91,628 4447 725,857 6.127 1.187 (1.144–1.232) 1.156 (1.114–1.200) 1.150 (1.108–1.193)
  ≥ 100/95 62,481 3511 491,435 7.144 1.503 (1.445–1.565) 1.419 (1.363–1.477) 1.371 (1.317–1.427)
  1. Model 1: adjusted for age and sex
  2. Model 2: adjusted for model 1 plus smoking, alcohol consumption, regular physical activity, social income, diabetes, hypertension, and dyslipidemia
  3. Model 3: adjusted for model 2 plus end stage renal failure, history of heart failure or coronary artery disease, hyperthyroidism, malignancy, and chronic obstructive pulmonary disease
  4. BMI body mass index, CI confidence interval, F female, IFG impaired fasting glucose, M male, WC waist circumference
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