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Table 1 Baseline clinical characteristics of patients with AMI matched by propensity score analysis

From: Pericoronary fat inflammation and Major Adverse Cardiac Events (MACE) in prediabetic patients with acute myocardial infarction: effects of metformin

  Normoglycemic patients Prediabetic patients P Prediabetic never metformin users Prediabetic current metformin users P
N 180 180   58 58  
Mean age (years) 68.2 ± 6.8 67.1 ± 6.3 0.082 66.2 ± 5.4 67.1 ± 4.9 0.345
Sex (M/F) 99/81 96/84 33/25 34/24
BMI (kg/m2) 27.1 ± 1.6 27.4 ± 1.9 0.088 27.3 ± 0.7 26.9 ± 1.2 0.140
Systolic blood pressure (mmHg) 130.8 ± 13.1 132.9 ± 10.9 0.064 131.2 ± 8.4 133.1 ± 7.7 0.945
Diastolic blood pressure (mmHg) 79.2 ± 6.5 79.3 ± 6.6 0.898 77.7 ± 6.4 79.4 ± 6.7 0.154
Heart rate (bpm) 87.2 ± 8.1 86.9 ± 8.6 0.744 85.9 ± 5.6 87.2 ± 8.8 0.357
Prediabetes diagnosis criteria
 Fasting plasma glucose, n (%) 39 (21.6) 10 (17.2) 11 (18.9) 0.488
 Post-prandial glucose, n (%) 18 (10) 11 (18.9) 10 (17.2) 0.502
 HbA1c, n (%) 102 (56.7) 24 (41.4) 25 (43.1) 0.493
 Two or more criteria, n (%) 21 (11.6) 13 (22.4) 12 (20.7) 0.559
Risk factors
 Hypertension, n (%) 143 (79.4) 144 (80.1) 0.500 49 (84.5) 51 (87.9) 0.394
 Hyperlipemia, n (%) 112 (62.2) 110 (61.1) 0.457 49 (84.5) 47 (81.1) 0.403
 Cigarette smoking, n (%) 141 (78.3) 142 (78.9) 0.500 47 (81.1) 51 (87.9) 0.221
Active treatments
 β-blockers, n (%) 104 (57.8) 106 (58.9) 0.457 43 (74.1) 41 (70.7) 0.418
 ACE inhibitors, n (%) 76 (42.2) 74 (41.1) 0.457 22 (37.9) 27 (46.6) 0.226
 Angiotensin receptor blockers, n (%) 88 (48.9) 75 (41.7) 0.102 25 (43.1) 22 (37.9) 0.353
 Calcium inhibitor, n (%) 100 (55.6) 105 (58.3) 0.335 37 (63.8) 41 (70.7) 0.277
 Nitrate, n (%) 46 (25.6) 34 (18.9) 0.081 7 (12.1) 9 (15.5) 0.394
 Statins, n (%) 92 (51.1) 100 (55.6) 0.230 32 (55.2) 28 (48.3) 0.289
 Thiazide diuretic, n (%) 55 (30.6) 56 (31.1) 0.500 22 (37.9) 25 (43.9) 0.353
 Aspirin, n (%) 115 (63.9) 118 (65.6) 0.413 37 (63.8) 38 (65.5) 0.500
 Thienopyridine, n (%) 24 (13.3) 24 (13.3) 0.562 6 (10.3) 7 (12.1) 0.500
Laboratory analyses
 Fasting plasma glucose (mg/dl) 86.5 ± 6.5 110 ± 7.3 0.001 111.5 ± 9.3 110.9 ± 7.6 0.762
 Post-prandial glucose (mg/dl) 106 ± 24 132 ± 36 0.001 131 ± 33 132 ± 29 0.658
 HbA1c (%) 5.1 ± 0.3 6.2 ± 03 0.001 6.1 ± 0.3 6.0 ± 0.4 0.463
 Cholesterol (mg/dl) 205.9 ± 21.1 205.1 ± 22.1 0.670 203.2 ± 19.1 206.6 ± 19.5 0.353
 LDL-cholesterol (mg/dl) 127.4 ± 20.9 131.3 ± 21.5 0.080 128.6 ± 29.4 133.1 ± 18.9 0.198
 HDL-cholesterol (mg/dl) 38.3 ± 3.5 38.1 ± 3.5 0.764 37.8 ± 3.3 37.5 ± 3.5 0.587
 Triglycerides (mg/dl) 181.5 ± 19.6 182.6 ± 22.1 0.621 185.1 ± 23.6 179.6 ± 17.3 0.154
 Creatinine (mg/dl) 0.99 ± 0.13 0.98 ± 0.19 0.399 0.98 ± 0.17 0.97 ± 0.16 0.833
 hs-cTnT (ng/l) 147.6 ± 32.7 149.6 ± 25.9 0.411 149.9 ± 32.1 149.2 ± 26.6 0.604
 Leptin (pg/ml) 27.9 ± 12.9 93.9 ± 28.1 0.001 111.1 ± 20.1 81.6 ± 24.8 0.001
 Adiponectin (pg/ml) 116.1 ± 22.5 58.1 ± 23.3 0.001 45.8 ± 19.3 70.9 ± 18.7 0.001
  1. Data are mean ± SD or n (%)