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Table 1 Baseline characteristics among 1414 patients with ACS

From: Genetic predisposition to type 2 diabetes is associated with severity of coronary artery disease in patients with acute coronary syndromes

Variables Total Single-vessel disease Multi-vessel disease P value
No. of patients n = 1414 n = 490 n = 924  
Demographics
 Age, median (IQR), years 60 (53–68) 58 (49–65) 61 (55–69) < 0.001
 BMI, median (IQR), kg/m2 24.7 (22.7–26.9) 24.7 (22.5–26.8) 24.7 (22.9–27.0) 0.325
 Male, n (%) 1112 (78.6) 380 (77.5) 732 (79.2) 0.509
 Current smoking, n (%) 588 (41.6) 201 (41.0) 387 (41.9) 0.798
Diagnosis, n (%)
 NSTEMI 271 (19.2) 89 (18.2) 182 (19.7)  
 STEMI 340 (24.0) 113 (23.1) 227 (24.6) 0.544
 UA 803 (56.8) 288 (58.8) 515 (55.7)  
Medical history, n (%)
 Hypertension 753 (53.3) 219 (44.7) 534 (57.8) < 0.001
 Type 2 diabetes 288 (20.4) 69 (14.1) 219 (23.7) < 0.001
 Hypercholesterolemia 255 (18.0) 81 (16.5) 174 (18.8) 0.318
 Prior myocardial infarction 121 (8.6) 34 (7.0) 87 (9.4) 0.138
 Prior revascularization 112 (7.9) 32 (6.5) 80 (8.6) 0.192
 Stroke/transient ischemic arrack (TIA) 71 (5.0) 19 (3.9) 52 (5.6) 0.192
 Heart failure 12 (0.8) 2 (0.4) 10 (1.1) 0.236
 Chronic angina 168 (11.9) 43 (8.8) 125 (13.5) 0.011
 Chronic renal failure 8 (0.6) 3 (0.6) 5 (0.5) 1.000
 Chronic obstructive pulmonary diseases (COPD)/other chronic lung diseases (CLD) 8 (0.6) 4 (0.8) 4 (0.4) 0.459
 Peripheral vascular disease 11 (0.8) 2 (0.4) 9 (1.0) 0.348
Genetic information
 Family history of CAD, n (%) 117 (8.3) 36 (7.3) 81 (8.8) 0.412
 T2D-GRS, median (IQR) 48.5 (46.0–51.1) 48.1 (45.5–50.5) 48.7 (46.3–51.3) < 0.001