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Table 1 Baseline characteristics of control, high-fat (HFa) diet-fed, and high-fructose/cholesterol (HFr) diet-fed rats

From: Atrial fibrillation and its arrhythmogenesis associated with insulin resistance

 

Control (n = 30)

HFa (n = 30)

HFr (n = 30)

0-week body weight (g)

305 ± 13.4

297 ± 8.2

293 ± 9.5

12-week body weight (g)

547 ± 55.8

678 ± 49.4*

555 ± 50.2

HW/BW (mg/g)

2.8 ± 0.5

2.4 ± 0.2*

2.8 ± 0.5

HR (bpm)

355 ± 10.2

380 ± 9.5

378 ± 8.5

MAP (mmHg)

77 ± 14.2

98 ± 9.9*

101 ± 14.3*

Blood glucose (mg/dL)

164 ± 19.9

196 ± 46.8*

214 ± 46.4*

Insulin (μg/L)

1.8 ± 0.9

4.6 ± 1.5*

4.3 ± 2.3*

Triglyceride (mg/dL)

59 ± 17.7

117 ± 38.8 *

118 ± 37.7*

Cholesterol (mg/dL)

75 ± 12.9

96 ± 9.5*

119 ± 25*

HDL (mg/dL)

27.5 ± 4.3

24.7 ± 3.8

32.8 ± 7.1*

HOMA-IR

24.3 ± 10.5

41.9 ± 12.1*

36 ± 12.5*

  1. HW heart weight, BW body weight, MAP mean arterial pressure, HDL high-density lipoprotein
  2. HOMA-IR = glucose (mg/dL) × insulin (mIU/L)/405
  3. *P < 0.05 vs. control
  4. Data are presented as mean ± SE