Skip to main content

Advertisement

Table 1 Baseline characteristics of the cohort

From: Metformin therapy in patients with diabetes mellitus is associated with a reduced risk of vasculopathy and cardiovascular mortality after heart transplantation

  Non-metformin N = 48 Metformin N = 55 p-value
Recipient age (years) (mean ± SD) 53 ± 11 54 ± 9 0.503
Donor age (years) (mean ± SD) 35 ± 13 33 ± 12 0.715
Recipient gender (male) (%) 42 (87) 47 (85) 0.989
Donor gender (male) (%) 23 (66) 29 (71) 0.825
Etiology (ischemic) (%) 38 (81) 35 (64) 0.089
Recipient BMI (kg/m2) (mean ± SD) 31 ± 33 27 ± 4 0.365
Donor BMI (kg/m2) (mean ± SD) 26 ± 5 27 ± 5 0.263
Hypertension (%) 27 (56) 36 (65) 0.451
Dyslipidemia (%) 28 (60) 43 (78) 0.069
Past smoker (%) 24 (50) 31 (56) 0.654
Assist device (%) 5 (10) 11 (20) 0.268
Status 1 (%) 26 (54) 29 (53) 1.000
PRA > 30% (%) 0 (0) 1 (2) 1.000
Recipient blood type (%)    0.664
 A 14 (41) 12 (32)  
 AB 5 (15) 4 (10)  
 B 5 (15) 9 (24)  
 O 10 (29) 13 (34)  
Recipient creatinine 1.5 ± 1.4 1.4 ± 0.6 0.524
Recipient bilirubin 1.7 ± 3.4 1.2 ± 0.9 0.317
Immunosuppression (%)    0.053
 1 38 (79) 31 (57)  
 2 10 (21) 22 (41)  
 3 0 (0) 1 (2)  
Ischemic time (min) (mean ± SD) 149 ± 39 165 ± 39 0.118
PAM (mmHg) (mean ± SD) 29 ± 12 27 ± 13 0.382
CO (mean ± SD) 3.6 ± 1 3.6 ± 1.1 0.972
PVR (mean ± SD) 3.1 ± 1.8 2.7 ± 1.6 0.394
CMV mismatch (%) 8 (29) 7 (26) 1.000
Statins post-HT (%) 46 (96) 53 (96) 1.000
Hypertension post-HT (%) 47 (98) 51 (93) 0.446
  1. SD standard deviation, BMI body mass index, PRA panel reactive antibody, PAM mean pulmonary pressure, CO cardiac output, PVR pulmonary vascular resistance, CMV cytomegalovirus, HT heart transplantation