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Table 5 Five-year outcomes according to diabetes status and revascularization assignment

From: Staged complete revascularization or culprit-only percutaneous coronary intervention for multivessel coronary artery disease in patients with ST-segment elevation myocardial infarction and diabetes

Clinical endpoint

No diabetes (n = 834)

Crude HR (95% CI)

Adjusted HR (95% CI)

Diabetes (n = 371)

Crude HR (95% CI)

Adjusted HR (95% CI)

P for interaction

Culprit-only PCI (n = 422)

Staged PCI (n = 412)

Culprit-only PCI (n = 207)

Staged PCI (n = 164)

MACCE

150 (35.5)

131 (31.8)

0.643(0.507–0.815)

0.638 (0.500–0.816)

66 (31.9)

62 (37.8)

0.939 (0.662–1.331)

0.986 (0.683–1.422)

0.053

Cardiac death/MI/stroke

64 (15.2)

47 (11.4)

0.529 (0.362–0.774)

0.621 (0.419–0.921)

23 (11.1)

23 (14.0)

1.042 (0.583–1.862)

1.593 (0.846–3.000)

0.013

All-cause death

39 (9.2)

41 (10.0)

0.808 (0.520–1.257)

1.281 (0.803–2.042)

18 (8.7)

14 (8.5)

0.709 (0.350–0.434)

0.876 (0.404–1.898)

0.410

Cardiac death

17 (4.0)

20 (4.9)

0.913 (0.476–1.753)

1.650 (0.817–3.335)

11 (5.3)

8 (4.9)

0.685 (0.274–1.717)

0.840 (0.304–2.316)

0.284

MI

39 (9.2)

19 (4.6)

0.346 (0.199–0.601)

0.358(0.200–0.641)

10 (4.8)

12 (7.3)

1.339 (0.578–3.103)

1.599 (0.663–3.858)

0.005

Stroke

12 (2.8)

8 (1.9)

0.517 (0.210–1.272)

0.574 (0.231–1.426)

6 (2.9)

5 (3.0)

0.878 (0.267–2.885)

0.857 (0.248–2.964)

0.610

Unplanned revascularization

105 (24.9)

82 (19.9)

0.625 (0.466–0.837)

0.532 (0.393–0.720)

45 (21.7)

43 (26.2)

1.045 (0.687–1.590)

1.038 (0.672–1.605)

0.013

  1. CI confidence interval, HR hazard ratio, MACCE major adverse cardiovascular and cerebrovascular event, MI myocardial infarction, PCI percutaneous coronary intervention