Table 1 Characteristics and biochemical indicators of pigs at the 18th week

n

10

10

10

BW (kg)

63.3 ± 7.2

79.6 ± 5.4^a

69.7 ± 6.5^a,b

HR (bpm)

74.2 ± 9.6

61.3 ± 7.8

75.9 ± 5.3

Plasma biochemistry

TC (mg/dl)

67.4 ± 3.3

543.5 ± 54.9^a

515.7 ± 49.7^a

LDL (mg/dl)

23.5 ± 3.1

352.7 ± 32.8^a

375.8 ± 26.8^a

HDL (mg/dl)

35.7 ± 2.3

196.4 ± 23.1^a

180.7 ± 28.3^a

TG (mg/dl)

28.6 ± 6.8

54.7 ± 13.1^a

59.6 ± 12.4^a

HbA1c (%)

5.3 ± 1.2

5.6 ± 0.8

5.5 ± 1.1

Urine biochemistry

Glucose (g/24 h)

0.1 ± 0.01

0.1 ± 0.01

24.0 ± 2.1^a,b

Na⁺ (mmol/24 h)

63.0 ± 5.4

54.6 ± 5.1^a

93.4 ± 8.5^a,b

Plasma ELISA (pg/ml)

BNP

56.9 ± 14.5

76.2 ± 15.3^a

77.3 ± 10.7^a

E

76.9 ± 14.5

125.2 ± 17.3^a

113.2 ± 28.7^a,b

NE

60.7 ± 14.3

179.6 ± 17.3^a

163.8 ± 20.9^a,b

Ang II

200.8 ± 19.7

476.5 ± 26.3^a

467.4 ± 33.1^a

Tissue ELISA (NE) (pg/ug)

LA

11.6 ± 4.2

19.8 ± 5.9^a

18.4 ± 3.5^a

LV

15.1 ± 3.6

29.7 ± 3.8^a

27.5 ± 8.7^a

Aorta

25.6 ± 7.9

71.4 ± 13.5^a

55.6 ± 11.9^a,b

Kidney

8.2 ± 3.1

16.3 ± 4.7^a

18.9 ± 3.0^a