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Table 3 Effects of add-on dapagliflozin therapy on home blood pressure profile

From: Improved home BP profile with dapagliflozin is associated with amelioration of albuminuria in Japanese patients with diabetic nephropathy: the Yokohama add-on inhibitory efficacy of dapagliflozin on albuminuria in Japanese patients with type 2 diabetes study (Y-AIDA study)

  Baseline Week 24 P value
Morning
 SBP (mmHg) 137.6 ± 14.5 129.7 ± 14.8 P < 0.001
 SBP-SD (mmHg) 8.8 ± 4.7 7.9 ± 3.8 P = 0.0496
 DBP (mmHg) 82.7 ± 10.3 78.7 ± 10.7 P < 0.001
 DBP-SD (mmHg) 5.2 ± 3.4 4.9 ± 3.0 P = 0.1494
 PR (beats/min) 72.9 ± 10.6 71.4 ± 10.8 P = 0.0785
Evening
 SBP (mmHg) 136.1 ± 17.4 127.2 ± 14.1 P < 0.001
 SBP-SD (mmHg) 9.4 ± 5.0 8.4 ± 4.0 P = 0.0143
 DBP (mmHg) 79.3 ± 10.1 75.0 ± 10.7 P < 0.001
 DBP-SD (mmHg) 5.7 ± 3.1 5.0 ± 2.5 P = 0.1331
 PR (beats/min) 76.5 ± 11.3 75.1 ± 11.0 P = 0.0414
Nocturnal
 SBP (mmHg) 125.4 ± 14.7 123.5 ± 15.1 P = 0.0079
 SBP-SD (mmHg) 8.9 ± 4.2 7.3 ± 3.2 P = 0.0049
 DBP (mmHg) 74.1 ± 9.5 72.8 ± 10.2 P = 0.0415
 DBP-SD (mmHg) 5.6 ± 2.8 4.7 ± 2.2 P = 0.0092
 PR (beats/min) 67.6 ± 11.2 65.6 ± 10.3 P = 0.0260
  1. Values are mean ± standard deviation (SD)
  2. SBP systolic blood pressure, DBP diastolic blood pressure, PR pulse rate