|
HOMA-IR tertiles
|
Low
|
Intermediate
|
High
|
P-value
|
|---|
|
LVEDD, mm
|
|
B
|
50.09 (4.35)
|
50.77 (5.00)
|
51.60 (5.23)
|
< 0.001
|
|
F
|
50.60 (4.99)
|
51.68 (5.49)
|
53.04 (5.33)
|
|
Δ
|
0.52 (2.47)
|
0.91 (3.08)
|
1.44 (3.96)
|
|
LVESD, mm
|
|
B
|
34.04 (5.09)
|
34.93 (5.35)
|
35.55 (5.40)
|
< 0.001
|
|
F
|
33.89 (5.43)
|
34.93 (6.14)
|
36.60 (6.37)
|
|
Δ
|
− 0.15 (3.351)
|
0.00 (2.94)
|
1.05 (4.11)
|
|
LVEDVI, mL/m2
|
|
B
|
70.17 (12.65)
|
69.61 (13.88)
|
70.28 (16.67)
|
< 0.001
|
|
F
|
72.09 (14.60)
|
72.66 (16.56)
|
75.00 (17.84)
|
|
Δ
|
1.91 (7.96)
|
3.06 (10.63)
|
4.66 (13.20)
|
|
LVESVI, mL/m2
|
|
B
|
29.11 (9.97)
|
29.46 (10.55)
|
30.32 (11.55)
|
< 0.001
|
|
F
|
28.65 (11.00)
|
29.86 (12.95)
|
32.28 (14.21)
|
|
Δ
|
− 0.46 (6.68)
|
0.40 (6.38)
|
1.96 (9.13)
|
|
LVMI, g/m2
|
|
B
|
93.55 (17.15)
|
96.39 (21.13)
|
96.21 (21.67)
|
0.130
|
|
F
|
94.47 (18.35)
|
95.32 (16.69)
|
93.66 (17.95)
|
|
Δ
|
0.91 (15.84)
|
− 1.07 (17.75)
|
− 2.73 (15.24)
|
|
IVST, mm
|
|
B
|
9.27 (1.04)
|
9.55 (1.15)
|
9.60 (1.10)
|
0.003
|
|
F
|
9.14 (1.11)
|
9.36 (1.04)
|
9.01 (1.16)
|
|
Δ
|
− 0.13 (1.21)
|
− 0.19 (1.22)
|
− 0.59 (1.48)
|
|
LVPWT, mm
|
|
B
|
8.92 (0.92)
|
9.20 (1.07)
|
9.19 (0.97)
|
0.006
|
|
F
|
8.93 (0.91)
|
8.92 (0.85)
|
8.83 (0.75)
|
|
Δ
|
0.01 (1.03)
|
− 0.28 (1.09)
|
− 0.37 (1.25)
|
|
RWT
|
|
B
|
0.36 (0.04)
|
0.37 (0.05)
|
0.37 (0.05)
|
0.001
|
|
F
|
0.36 (0.04)
|
0.36 (0.05)
|
0.34 (0.05)
|
|
Δ
|
− 0.01 (0.05)
|
− 0.01 (0.04)
|
− 0.03 (0.06)
|
|
LVEF, %
|
|
B
|
59.04 (8.03)
|
58.20 (7.85)
|
57.76 (7.35)
|
0.089
|
|
F
|
60.89 (7.63)
|
59.99 (7.53)
|
58.22 (8.36)
|
|
Δ
|
1.85 (6.76)
|
1.79 (5.40)
|
0.47 (6.80)
|
- Values are given as mean (standard deviation)
- B baseline, Δ changes in corresponding parameters, F follow-up, IVST interventricular septal thickness, LVEDD left ventricular end-diastolic diameter, LVEDVI left ventricular end-diastolic volume indexed to body surface area, LVEF left ventricular ejection fraction, LVESD left ventricular end-systolic diameter, LVESVI left ventricular end-systolic volume indexed to body surface area, LVMI left ventricular mass indexed to body surface area, LVPWT left ventricular posterior wall thickness, RWT relative wall thickness
