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Table 2 Bivariate unadjusted analysis of the plaque at baseline according to the incidence of cardiovascular events

From: Subclinical atherosclerosis burden predicts cardiovascular events in individuals with diabetes and chronic kidney disease

  CKD without diabetes CKD with diabetes
No CVE N = 1640 CVE N = 107 HR [95% CI] p value* No CVE N = 602 CVE N = 96 HR [95% CI] p value*
Territories with plaque 1.0 [0.0;3.0] 3.0 [2.0;5.0] 1.26 [1.18;1.35] < 0.001 2.0 [1.0;5.0] 4.0 [2.0;6.0] 1.18 [1.09;1.27] < 0.001
Presence of plaque 1040 (63.4%) 98 (91.6%) 5.83 [2.95;11.54] < 0.001 480 (79.7%) 90 (93.8%) 3.39 [1.48;7.75] 0.004
Presence of carotid plaque 815 (49.7%) 86 (80.4%) 3.80 [2.36;6.12] < 0.001 418 (69.4%) 84 (87.5%) 2.86 [1.56;5.24] 0.001
Carotid plaque [only] 267 (16.3%) 24 (22.4%) 1.41 [0.90;2.22] 0.137 143 (23.8%) 22 (22.9%) 0.92 [0.57;1.49] 0.748
Presence of femoral plaque 773 (47.1%) 74 (69.2%) 2.42 [1.60;3.64] < 0.001 337 (56.0%) 68 (70.8%) 1.81 [1.17;2.82] 0.008
Femoral plaque [only] 225 (13.7%) 12 (11.2%) 0.83 [0.45;1.51] 0.538 62 (10.3%) 6 (6.25%) 0.56 [0.25;1.29] 0.173
> 2 territories with plaque 772 (47.1%) 81 (75.7%) 3.26 [2.09;5.07] < 0.001 382 (63.5%) 83 (86.5%) 3.35 [1.87;6.01] < 0.001
Carotid and femoral plaque 548 (33.4%) 62 (57.9%) 2.57 [1.75;3.78] < 0.001 275 (45.7%) 62 (64.6%) 2.09 [1.37;3.17] 0.001
  1. CVE fatal and non-fatal cardiovascular event
  2. *p values correspond to HR. Chi-squared test for trend in proportions p < 0.005