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Table 2 Bivariate unadjusted analysis of the plaque at baseline according to the incidence of cardiovascular events

From: Subclinical atherosclerosis burden predicts cardiovascular events in individuals with diabetes and chronic kidney disease

 

CKD without diabetes

CKD with diabetes

No CVE N = 1640

CVE N = 107

HR [95% CI]

p value*

No CVE N = 602

CVE N = 96

HR [95% CI]

p value*

Territories with plaque

1.0 [0.0;3.0]

3.0 [2.0;5.0]

1.26 [1.18;1.35]

< 0.001

2.0 [1.0;5.0]

4.0 [2.0;6.0]

1.18 [1.09;1.27]

< 0.001

Presence of plaque

1040 (63.4%)

98 (91.6%)

5.83 [2.95;11.54]

< 0.001

480 (79.7%)

90 (93.8%)

3.39 [1.48;7.75]

0.004

Presence of carotid plaque

815 (49.7%)

86 (80.4%)

3.80 [2.36;6.12]

< 0.001

418 (69.4%)

84 (87.5%)

2.86 [1.56;5.24]

0.001

Carotid plaque [only]

267 (16.3%)

24 (22.4%)

1.41 [0.90;2.22]

0.137

143 (23.8%)

22 (22.9%)

0.92 [0.57;1.49]

0.748

Presence of femoral plaque

773 (47.1%)

74 (69.2%)

2.42 [1.60;3.64]

< 0.001

337 (56.0%)

68 (70.8%)

1.81 [1.17;2.82]

0.008

Femoral plaque [only]

225 (13.7%)

12 (11.2%)

0.83 [0.45;1.51]

0.538

62 (10.3%)

6 (6.25%)

0.56 [0.25;1.29]

0.173

> 2 territories with plaque

772 (47.1%)

81 (75.7%)

3.26 [2.09;5.07]

< 0.001

382 (63.5%)

83 (86.5%)

3.35 [1.87;6.01]

< 0.001

Carotid and femoral plaque

548 (33.4%)

62 (57.9%)

2.57 [1.75;3.78]

< 0.001

275 (45.7%)

62 (64.6%)

2.09 [1.37;3.17]

0.001

  1. CVE fatal and non-fatal cardiovascular event
  2. *p values correspond to HR. Chi-squared test for trend in proportions p < 0.005
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Cardiovascular Diabetology

ISSN: 1475-2840