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Table 2 Results of univariable and multivariabe Cox regression analyses

From: Carotid ultrasound investigation as a prognostic tool for patients with diabetes mellitus

Variable   All-cause mortality Cardiovascular mortality
Hazard ratio CI P-value Hazard ratio CI P-value
Univariable n  
 Diabetes mellitus 335 1.14 1.06–1.22 < 0.001 1.14 1.08–1.22 < 0.001
 Per increase of 1% of hba1c 1065 1.23 1.15–1.32 < 0.001 1.30 1.20–1.41 < 0.001
 Carotid stenosis ≥ 50% 374 1.67 1.40–1.97 < 0.001 1.70 1.39–2.08 < 0.001
Combined model
 Carotid stenosis < 50%; Ø DMa 522 Ref      
 Carotid stenosis ≥ 50%; Ø DM 276 1.65 1.33–2.06 < 0.001 1.71 1.30–2.25 < 0.001
 Carotid stenosis < 50%; DM 166 1.86 1.48–2.34 < 0.001 2.13 1.61–2.81 < 0.001
 Carotid stenosis ≥ 50%; DM 101 3.23 2.53–4.13 < 0.001 3.67 2.73–4.94 < 0.001
Multivariable
 Diabetes mellitus 335 1.14 1.06–1.22 < 0.001 1.14 1.08–1.22 < 0.001
 Per increase of 1% of hba1c 1065 1.21 1.12–1.32 < 0.001 1.30 1.20–1.43 < 0.001
 Carotid stenosis ≥ 50% 374 1.28 1.30 0.004 1.28 1.03–1.60 0.025
Combined model
 Carotid stenosis < 50%; Ø DMa 522 Ref      
 Carotid stenosis ≥ 50%; Ø DM 276 1.27 1.01–1.59 0.040 1.26 0.96–1.64 0.072
 Carotid stenosis < 50%; DM 166 1.56 1.22–1.99 < 0.001 1.78 1.33–2.39 < 0.001
 Carotid stenosis ≥ 50%; DM 101 2.22 1.71–2.99 < 0.001 2.35 1.71–3.24 < 0.001
  1. CI confidence interval, HR hazard ratio, hsCRP high sensitivity C-reactive protein
  2. aReference category; adjusted for age, sex, body mass index, hypertension smoking, history of peripheral artery disease, history of stroke history of myocardial infarction, low-density lipoprotein cholesterol levels, triglyceride levels, statin treatment, serum creatinine, hsCRP