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Table 2 Risk factors during pregnancy for developing characteristics of the metabolic syndrome—multivariate analysis

From: Good glycemic control of gestational diabetes mellitus is associated with the attenuation of future maternal cardiovascular risk: a retrospective cohort study

Risk factor

Adjusted HR [95% CI]

p value

Type 2 diabetes mellitus

 Poor glycemic control vs. controls

14.8 [7.6–28.8]

< 0.0001

 Good glycemic control vs. controls

8.4 [4.3–16.6]

< 0.0001

 Poor glycemic control vs. good glycemic control

1.7 [1.3–2.4]

0.0004

 Pre-pregnancy body mass index (BMI)

1.04 [1.01–1.1]

0.004

 Parity

1.2 [1.1–1.2]

< 0.0001

Dyslipidemia

 Poor glycemic control vs. controls

3.7 [2.3–5.9]

< 0.0001

 Good glycemic control vs. controls

2.0 [1.3–3.3]

0.004

 Poor glycemic control vs. good glycemic control

1.8 [1.3–2.6]

0.0003

 Pre-pregnancy BMI

1.05 [1.02–1.07]

< 0.0001

Obesity

 Pre-pregnancy BMI

1.09 [1.07–1.1]

< 0.0001

Hypertension

 Pre-pregnancy BMI

1.04 [1.004–1.07]

0.04

 Maternal age during pregnancy

1.1 [1.07–1.20]

< 0.0001

  1. Stepwise multiple Cox regression model to evaluate independent risk factors for developing type 2 diabetes mellitus: hypertension, obesity, and dyslipidemia. Controls refer to women without gestational diabetes mellitus during pregnancy. Good glycemic control refers to mean daily glucose charts ≤ 95 mg/dL. Poor glycemic control refers to mean daily glucose charts > 95 mg/dL
  2. HR hazard ratio