From: Canagliflozin for Japanese patients with chronic heart failure and type II diabetes
Pre | 6 months | 12 months | |
---|---|---|---|
S-BP (mmHg) | 136.2 ± 2.7 | 127.5 ± 3.0* | 130.1 ± 3.2 |
D-BP (mmHg) | 76.9 ± 1.2 | 72.7 ± 1.7* | 75.2 ± 1.9 |
Heart rate (/min) | 66.9 ± 1.6 | 65.5 ± 2.2 | 68.2 ± 1.3 |
Right PWV (cm/s) | 1821.7 ± 70.6 | 1713.9 ± 64.0* | 1784.1 ± 67.0 |
left PWV (cm/s) | 1883.1 ± 82.5 | 1715.2 ± 69.4* | 1814.4 ± 76.7 |
Right ABI | 1.15 ± 0.02 | 1.14 ± 0.02 | 1.12 ± 0.03 |
Left ABI | 1.15 ± 0.02 | 1.14 ± 0.02 | 1.12 ± 0.02 |
Echocardiography | |||
LVDd (mm) | 47.1 ± 1.1 | 45.7 ± 0.9 | 46.3 ± 1.0 |
LVDs (mm) | 31.6 ± 0.8 | 30.4 ± 0.7* | 29.9 ± 0.8* |
Ejection fraction (%) | 60.9 ± 1.6 | 61.9 ± 1.5 | 64.6 ± 1.3*$ |
% fractional shortening (%) | 33.0 ± 0.9 | 33.4 ± 1.0 | 35.4 ± 0.9*$ |
LVMI (g/m2) | 166.5 ± 6.4 | 147.7 ± 5.8* | 140.6 ± 5.4*$ |