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Table 6 Multivariable analysis of factors associated with MACCE among type 2 diabetes and non-type 2 diabetes patients who underwent bioprosthetic mitral valve replacement

From: Impact of type 2 diabetes mellitus in the utilization and in-hospital outcomes of surgical mitral valve replacement in Spain (2001–2015)

  T2DM Non-T2DM Both
OR (95% CI) p-value OR (95% CI) p-value OR (95% CI) p-value
Age 1.03 (1.01–1.05) 0.013 1.02 (1.01–1.03) 0.003 1.02 (1.01–1.03) 0.002
Female sex 1.03 (0.73–1.44) 0.677 1.27 (1.08–1.49) 0.009 1.21 (1.04–1.39) 0.008
Coronary artery bypass graft 1.54 (1.07–2.21) 0.020 1.74 (1.45–2.08) < 0.001 1.71 (1.45–2.00) < 0.001
Intra-aortic balloon counter-pulsation 9.64 (5.60–16.58) < 0.001 9.21 (7.01–12.09) < 0.001 9.46 (7.41–12.06) < 0.001
Pacemaker implantation 0.39 (0.16–0.90) 0.029 0.46 (0.32–0.67) < 0.001 0.44 (0.32–0.62) < 0.001
Blood transfusion NS NS 1.36 (1.16–1.60) < 0.001 1.36 (1.18–1.58) < 0.001
Acute renal disease 3.67 (2.56–5.28) < 0.001 3.01 (2.54–3.57) < 0.001 3.00 (2.57–3.50) < 0.001
Congestive heart failure 2.30 (1.65–3.22) < 0.001 1.82 (1.56–2.13) < 0.001 1.89 (1.64–2.18) < 0.001
Atrial fibrillation 0.66 (0.48–0.93) 0.017 0.59 (0.50–0.68) < 0.001 0.59 (0.52–0.68) < 0.001
Pulmonary hypertension NS NS 0.83 (0.70–0.98) 0.031 0.84 (0.72–0.99) 0.034
Obesity NS NS 0.54 (0.36–0.82) 0.004 0.66 (0.48–0.91) 0.011
Endocarditis NS NS 1.49 (1.25–1.79) < 0.001 1.49 (1.27–1.75) < 0.001
Pneumonia 2.91 (1.33–6.37) 0.007 2.96 (2.19–4.03) < 0.001 3.00 (2.26–3.99) < 0.001
Renal disease 1.61 (1.05–2.46) 0.029 NS NS 1.27 (1.04–1.56) 0.021
Liver disease 2.58 (1.29–5.17) 0.007 3.22 (2.36–4.40) < 0.001 3.09 (2.33–4.11) < 0.001
Year 0.95 (0.91–0.99) 0.018 0.93 (0.92–0.95) < 0.001 0.93 (0.92–0.95) < 0.001
T2DM NS NS NS NS 0.88 (0.74–1.05) 0.172
  1. T2DM type 2 diabetes mellitus, NS not significant