Table 5 Multivariable analysis of factors associated with MACCE among type 2 diabetes and non-type 2 diabetes patients who underwent mechanical mitral valve replacement

Age

1.02 (1.01–1.04)

< 0.001

1.04 (1.03–1.05)

< 0.001

1.04 (1.03–1.05)

< 0.001

Female sex

1.01 (0.85–1.20)

0.882

0.91 (0.84–0.99)

0.013

0.92 (0.86–0.99)

0.028

Coronary artery bypass graft

1.32 (1.07–1.61)

0.008

1.83 (1.65–2.03)

< 0.001

1.69 (1.55–1.85)

< 0.001

Intra-aortic balloon counter-pulsation

7.10 (5.16–9.78)

< 0.001

8.06 (6.96–9.35)

< 0.001

7.88 (6.89–9.01)

< 0.001

Pacemaker implantation

NS

NS

0.62 (0.51–0.76)

< 0.001

0.69 (0.59–0.83)

< 0.001

Blood transfusion

1.34 (1.12–1.59)

0.001

1.49 (1.38–1.62)

< 0.001

1.46 (1.36–1.58)

< 0.001

Peripheral vascular disease

NS

NS

1.33 (1.11–1.60)

0.002

1.29 (1.10–1.52)

0.002

Acute renal disease

4.14 (3.39–5.05)

< 0.001

4.04 (3.68–4.43)

< 0.001

4.07 (3.74–4.42)

< 0.001

Congestive heart failure

1.59 (1.33–1.90)

< 0.001

1.79 (1.65–1.95)

< 0.001

1.76 (1.63–1.89)

< 0.001

Atrial fibrillation

0.57 (0.49–0.67)

< 0.001

0.54 (0.50–0.58)

< 0.001

0.54 (0.51–0.58)

< 0.001

Pulmonary hypertension

NS

NS

0.85 (0.78–0.93)

< 0.001

0.86 (0.80–0.93)

< 0.001

Obesity

NS

NS

0.71 (0.59–0.84)

< 0.001

0.83 (0.72–0.96)

0.011

Gastrointestinal hemorrhage

NS

NS

2.81 (1.88–4.19)

< 0.001

2.52 (1.733.68)

< 0.001

Endocarditis

1.85 (1.47–2.33)

< 0.001

1.64 (1.48–1.83)

< 0.001

1.67 (1.52–1.85)

< 0.001

Pneumonia

2.77 (1.86–4.14)

< 0.001

3.44 (2.93–4.05)

< 0.001

3.35 (2.89–3.90)

< 0.001

Renal disease

1.59 (1.26–2.01)

< 0.001

1.29 (1.12–1.48)

< 0.001

1.34 (1.19–1.51)

< 0.001

Liver disease

3.07 (2.24–4.19)

< 0.001

3.11 (2.66–3.64)

< 0.001

3.13 (2.72–3.60)

< 0.001

Cancer

NS

NS

1.56 (1.14–2.14)

0.006

NS

NS

Weight loss

3.21 (1.36–7.56)

0.008

NS

NS

NS

NS

Year

0.92 (0.90–0.94)

< 0.001

0.95 (0.93–0.95)

< 0.001

0.94 (0.93–0.95)

< 0.001

T2DM

NS

NS

NS

NS

0.96 (0.87–1.05)

0.338