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Table 5 Multivariable analysis of factors associated with MACCE among type 2 diabetes and non-type 2 diabetes patients who underwent mechanical mitral valve replacement

From: Impact of type 2 diabetes mellitus in the utilization and in-hospital outcomes of surgical mitral valve replacement in Spain (2001–2015)

  T2DM Non-T2DM Both
OR (95% CI) p-value OR (95% CI) p-value OR (95% CI) p-value
Age 1.02 (1.01–1.04) < 0.001 1.04 (1.03–1.05) < 0.001 1.04 (1.03–1.05) < 0.001
Female sex 1.01 (0.85–1.20) 0.882 0.91 (0.84–0.99) 0.013 0.92 (0.86–0.99) 0.028
Coronary artery bypass graft 1.32 (1.07–1.61) 0.008 1.83 (1.65–2.03) < 0.001 1.69 (1.55–1.85) < 0.001
Intra-aortic balloon counter-pulsation 7.10 (5.16–9.78) < 0.001 8.06 (6.96–9.35) < 0.001 7.88 (6.89–9.01) < 0.001
Pacemaker implantation NS NS 0.62 (0.51–0.76) < 0.001 0.69 (0.59–0.83) < 0.001
Blood transfusion 1.34 (1.12–1.59) 0.001 1.49 (1.38–1.62) < 0.001 1.46 (1.36–1.58) < 0.001
Peripheral vascular disease NS NS 1.33 (1.11–1.60) 0.002 1.29 (1.10–1.52) 0.002
Acute renal disease 4.14 (3.39–5.05) < 0.001 4.04 (3.68–4.43) < 0.001 4.07 (3.74–4.42) < 0.001
Congestive heart failure 1.59 (1.33–1.90) < 0.001 1.79 (1.65–1.95) < 0.001 1.76 (1.63–1.89) < 0.001
Atrial fibrillation 0.57 (0.49–0.67) < 0.001 0.54 (0.50–0.58) < 0.001 0.54 (0.51–0.58) < 0.001
Pulmonary hypertension NS NS 0.85 (0.78–0.93) < 0.001 0.86 (0.80–0.93) < 0.001
Obesity NS NS 0.71 (0.59–0.84) < 0.001 0.83 (0.72–0.96) 0.011
Gastrointestinal hemorrhage NS NS 2.81 (1.88–4.19) < 0.001 2.52 (1.733.68) < 0.001
Endocarditis 1.85 (1.47–2.33) < 0.001 1.64 (1.48–1.83) < 0.001 1.67 (1.52–1.85) < 0.001
Pneumonia 2.77 (1.86–4.14) < 0.001 3.44 (2.93–4.05) < 0.001 3.35 (2.89–3.90) < 0.001
Renal disease 1.59 (1.26–2.01) < 0.001 1.29 (1.12–1.48) < 0.001 1.34 (1.19–1.51) < 0.001
Liver disease 3.07 (2.24–4.19) < 0.001 3.11 (2.66–3.64) < 0.001 3.13 (2.72–3.60) < 0.001
Cancer NS NS 1.56 (1.14–2.14) 0.006 NS NS
Weight loss 3.21 (1.36–7.56) 0.008 NS NS NS NS
Year 0.92 (0.90–0.94) < 0.001 0.95 (0.93–0.95) < 0.001 0.94 (0.93–0.95) < 0.001
T2DM NS NS NS NS 0.96 (0.87–1.05) 0.338
  1. T2DM type 2 diabetes mellitus, NS not significant
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Cardiovascular Diabetology

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