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Table 3 Incidence and sociodemographic and clinical characteristics of patients hospitalized who underwent a bioprosthetic mitral valve replacement in Spain from 2001 to 2015 according to type 2 diabetes status

From: Impact of type 2 diabetes mellitus in the utilization and in-hospital outcomes of surgical mitral valve replacement in Spain (2001–2015)

  T2DM 2001–2005 2006–2010 2011–2015 Total Trend
Number of procedures (incidence per 100,000 inhabitants)* Yes 219 (2.22) 449 (3.98) 627 (4.78) 1295 (3.78) < 0.001
No 1134 (1.27) 1898 (1.89) 2706 (2.53) 5738 (1.93) < 0.001
Both 1353 (1.37) 2347 (2.10) 3333 (2.78) 7033 (2.13) < 0.001
Age, mean (SD) Yes 72.45 (5.84) 74.09 (5.52) 74.29 (5.75) 73.91 (5.72) 0.012
No 72.14 (7.45) 73.17 (7.48) 74.42 (6.81) 73.55 (7.22) < 0.001
Female sex, n (%) Yes 129 (58.9) 280 (62.36) 382 (60.93) 791 (61.08) 0.686
No 664 (58.55) 1098 (57.85) 1576 (58.24) 3338 (58.17) 0.926
Coronary artery bypass graft, n (%)* Yes 59 (26.94) 112 (24.94) 137 (21.85) 308 (23.78) 0.243
No 192 (16.93) 320 (16.86) 472 (17.44) 984 (17.15) 0.855
Surgical aortic valve replacement, n (%) Yes 59 (26.94) 154 (34.3) 219 (34.93) 432 (33.36) 0.085
No 354 (31.22) 658 (34.67) 995 (36.77) 2007 (34.98) 0.004
Other valve procedures on pulmonary or tricuspid valves, n (%) Yes 38 (17.35) 110 (24.5) 186 (29.67) 334 (25.79) 0.001
No 225 (19.84) 519 (27.34) 826 (30.52) 1570 (27.36) < 0.001
Intra-aortic balloon counter-pulsation, n (%) Yes 14 (6.39) 40 (8.91) 30 (4.78) 84 (6.49) 0.025
No 46 (4.06) 110 (5.8) 154 (5.69) 310 (5.4) 0.081
Pacemaker implantation, n (%) Yes 21 (9.59) 26 (5.79) 43 (6.86) 90 (6.95) 0.192
No 61 (5.38) 119 (6.27) 193 (7.13) 373 (6.5) 0.117
Blood transfusion, n (%) Yes 47 (21.46) 110 (24.5) 188 (29.98) 345 (26.64) 0.022
No 270 (23.81) 459 (24.18) 803 (29.67) 1532 (26.7) < 0.001
Length of hospital stay, mean (SD) Yes 26.68 (19.57) 25.09 (22.3) 20.92 (20.68) 23.34 (21.2) 0.007
No 26.97 (25.33) 25.32 (24.46) 23.35 (22.19) 24.72 (23.64) 0.001
In-hospital mortality, n (%) Yes 39 (17.81) 70 (15.59) 76 (12.12) 185 (14.29) 0.073
No 192 (16.93) 312 (16.44) 364 (13.45) 868 (15.13) 0.003
MACCE, n (%) Yes 50 (22.83) 83 (18.49) 103 (16.43) 236 (18.22) 0.106
No 250 (22.05) 408 (21.5) 469 (17.33) 1127 (19.64) < 0.001
  1. MACCE include in-hospital all-cause death, acute myocardial infarction or ischemic stroke
  2. T2DM type 2 diabetes mellitus
  3. * p < 0.05 for comparisons between T2DM patients and non-T2DM patients