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Table 4 Associations between lipid parameters and UACR in women

From: Elevated triglycerides rather than other lipid parameters are associated with increased urinary albumin to creatinine ratio in the general population of China: a report from the REACTION study

Variable Model 1 Model 2 Model 3 Model 4 Model 5
OR (95% CI) P value OR (95% CI) P value OR (95% CI) P value OR (95% CI) P value OR (95% CI) P value
TG, mmol/L
 < 1.7 Reference Reference Reference Reference Reference
 1.7–2.2 1.098 (1.028, 1.173) 0.006 1.097 (1.025, 1.174) 0.008 1.093 (1.021, 1.170) 0.011 1.070 (0.999, 1.146) 0.053 1.000 (0.933, 1.072) 0.994
 ≥ 2.3 1.313 (1.222, 1.410) < 0.001 1.296 (1.202, 1.397) < 0.001 1.290 (1.197, 1.391) < 0.001 1.263 (1.171, 1.362) < 0.001 1.129 (1.046, 1.219) 0.002
TC, mmol/L
 < 5.2 Reference Reference Reference Reference Reference
 5.2–6.1 0.954 (0.885, 1.028) 0.218 0.941 (0.872, 1.016) 0.123 0.944 (0.874, 1.019) 0.138 0.953 (0.883, 1.029) 0.222 0.941 (0.871, 1.017) 0.123
 ≥ 6.2 0.806 (0.707, 0.920) 0.001 0.797 (0.696, 0.912) 0.001 0.798 (0.698, 0.913) 0.001 0.820 (0.716, 0.938) 0.004 0.812 (0.709, 0.930) 0.003
LDL-C, mmol/L
 < 3.4 Reference Reference Reference Reference Reference
 3.4–4.0 1.270 (1.023, 1.578) 0.031 1.300 (1.043, 1.620) 0.019 1.298 (1.042, 1.618) 0.02 1.303 (1.046, 1.624) 0.018 1.206 (0.966, 1.506) 0.097
 ≥ 4.1 1.239 (0.768, 1.998) 0.379 1.301 (0.806, 2.100) 0.281 1.293 (0.801, 2.087) 0.294 1.308 (0.810, 2.112) 0.272 1.255 (.0.774, 2.036) 0.357
HDL-C, mmol/L
 ≥ 1.0 Reference Reference Reference Reference Reference
 < 1.0 1.064 (0.990, 1.144) 0.09 1.044 (0.961, 1.135) 0.307 1.041 (0.958, 1.131) 0.347 1.023 (0.941, 1.112) 0.594 0.987 (0.908, 1.074) 0.765
Non-HDL-C, mmol/L
 < 4.1 Reference Reference Reference Reference Reference
 4.1–4.8 1.099 (1.010, 1.196) 0.029 1.103 (1.012, 1.203) 0.026 1.103 (1.012, 1.203) 0.026 1.086 (0.996, 1.184) 0.061 1.061 (0.973, 1.158) 0.18
 ≥ 4.9 1.215 (1.055, 1.399) 0.007 1.200 (1.039, 1.385) 0.013 1.201 (1.040, 1.387) 0.013 1.171 (1.013, 1.352) 0.032 1.103 (0.954, 1.275) 0.184
  1. Model 1: adjusted for age, centres
  2. Model 2: additionally adjusted for ALT, AST, GGT, eGFR
  3. Model 3: additionally adjusted for smoking, drinking, MI, stroke, CHD
  4. Model 4: additionally adjusted for BMI
  5. Model 5: additionally adjusted for HbA1c, SBP, DBP
  6. Italic values indicate significance of P value (P < 0.05)
  7. UACR: urinary albumin to creatinine ratio; TG: triglycerides; TC: total cholesterol; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; Non-HDL-C: non-high-density lipoprotein cholesterol