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Table 4 Associations between lipid parameters and UACR in women

From: Elevated triglycerides rather than other lipid parameters are associated with increased urinary albumin to creatinine ratio in the general population of China: a report from the REACTION study

Variable

Model 1

Model 2

Model 3

Model 4

Model 5

OR (95% CI)

P value

OR (95% CI)

P value

OR (95% CI)

P value

OR (95% CI)

P value

OR (95% CI)

P value

TG, mmol/L

 < 1.7

Reference

Reference

Reference

Reference

Reference

 1.7–2.2

1.098 (1.028, 1.173)

0.006

1.097 (1.025, 1.174)

0.008

1.093 (1.021, 1.170)

0.011

1.070 (0.999, 1.146)

0.053

1.000 (0.933, 1.072)

0.994

 ≥ 2.3

1.313 (1.222, 1.410)

< 0.001

1.296 (1.202, 1.397)

< 0.001

1.290 (1.197, 1.391)

< 0.001

1.263 (1.171, 1.362)

< 0.001

1.129 (1.046, 1.219)

0.002

TC, mmol/L

 < 5.2

Reference

Reference

Reference

Reference

Reference

 5.2–6.1

0.954 (0.885, 1.028)

0.218

0.941 (0.872, 1.016)

0.123

0.944 (0.874, 1.019)

0.138

0.953 (0.883, 1.029)

0.222

0.941 (0.871, 1.017)

0.123

 ≥ 6.2

0.806 (0.707, 0.920)

0.001

0.797 (0.696, 0.912)

0.001

0.798 (0.698, 0.913)

0.001

0.820 (0.716, 0.938)

0.004

0.812 (0.709, 0.930)

0.003

LDL-C, mmol/L

 < 3.4

Reference

Reference

Reference

Reference

Reference

 3.4–4.0

1.270 (1.023, 1.578)

0.031

1.300 (1.043, 1.620)

0.019

1.298 (1.042, 1.618)

0.02

1.303 (1.046, 1.624)

0.018

1.206 (0.966, 1.506)

0.097

 ≥ 4.1

1.239 (0.768, 1.998)

0.379

1.301 (0.806, 2.100)

0.281

1.293 (0.801, 2.087)

0.294

1.308 (0.810, 2.112)

0.272

1.255 (.0.774, 2.036)

0.357

HDL-C, mmol/L

 ≥ 1.0

Reference

Reference

Reference

Reference

Reference

 < 1.0

1.064 (0.990, 1.144)

0.09

1.044 (0.961, 1.135)

0.307

1.041 (0.958, 1.131)

0.347

1.023 (0.941, 1.112)

0.594

0.987 (0.908, 1.074)

0.765

Non-HDL-C, mmol/L

 < 4.1

Reference

Reference

Reference

Reference

Reference

 4.1–4.8

1.099 (1.010, 1.196)

0.029

1.103 (1.012, 1.203)

0.026

1.103 (1.012, 1.203)

0.026

1.086 (0.996, 1.184)

0.061

1.061 (0.973, 1.158)

0.18

 ≥ 4.9

1.215 (1.055, 1.399)

0.007

1.200 (1.039, 1.385)

0.013

1.201 (1.040, 1.387)

0.013

1.171 (1.013, 1.352)

0.032

1.103 (0.954, 1.275)

0.184

  1. Model 1: adjusted for age, centres
  2. Model 2: additionally adjusted for ALT, AST, GGT, eGFR
  3. Model 3: additionally adjusted for smoking, drinking, MI, stroke, CHD
  4. Model 4: additionally adjusted for BMI
  5. Model 5: additionally adjusted for HbA1c, SBP, DBP
  6. Italic values indicate significance of P value (P < 0.05)
  7. UACR: urinary albumin to creatinine ratio; TG: triglycerides; TC: total cholesterol; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; Non-HDL-C: non-high-density lipoprotein cholesterol
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Cardiovascular Diabetology

ISSN: 1475-2840