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Table 3 Associations between lipid parameters and UACR in men

From: Elevated triglycerides rather than other lipid parameters are associated with increased urinary albumin to creatinine ratio in the general population of China: a report from the REACTION study

Variable Model 1 Model 2 Model 3 Model 4 Model 5
OR (95% CI) P value OR (95% CI) P value OR (95% CI) P value OR (95% CI) P value OR (95% CI) P value
TG, mmol/L
 < 1.7 Reference Reference Reference Reference Reference
 1.7–2.2 1.226 (1.116, 1.346) < 0.001 1.178 (1.069, 1.298) 0.001 1.179 (1.070, 1.299) 0.001 1.142 (1.036, 1.259) 0.008 1.075 (0.974, 1.186) 0.151
 ≥ 2.3 1.408 (1.279, 1.549) < 0.001 1.297 (1.172, 1.436) < 0.001 1.292 (1.167, 1.430) < 0.001 1.250 (1.129, 1.385) < 0.001 1.134 (1.022, 1.258) 0.017
TC, mmol/L
 < 5.2 Reference Reference Reference Reference Reference
 5.2–6.1 1.046 (0.920, 1.189) 0.492 1.018 (0.893, 1.160) 0.793 1.030 (0.903, 1.174) 0.660 1.041 (0.913, 1.186) 0.553 1.007 (0.882, 1.150) 0.916
 ≥ 6.2 0.943 (0.748, 1.188) 0.616 0.899 (0.711, 1.137) 0.376 0.910 (0.719, 1.151) 0.430 0.939 (0.742, 1.188) 0.599 0.872 (0.687, 1.107) 0.260
LDL-C, mmol/L
 < 3.4 Reference Reference Reference Reference Reference
 3.4–4.0 0.964 (0.617, 1.506) 0.872 0.939 (0.597, 1.476) 0.784 0.914 (0.580, 1.438) 0.697 0.941 (0.598, 1.482) 0.794 1.004 (0.635, 1.586) 0.987
 ≥ 4.1 1.309 (0.505, 3.393) 0.579 1.376 (0.530, 3.569) 0.512 1.437 (0.554, 3.728) 0.457 1.486 (0.573, 3.855) 0.416 1.623 (0.615, 4.284) 0.328
HDL-C mmol/L
 ≥1.0 Reference Reference Reference Reference Reference
 < 1.0 1.092 (1.008, 1.183) 0.030 1.109 (1.018, 1.208) 0.017 1.099 (1.008, 1.197) 0.031 1.060 (0.972, 1.155) 0.188 1.065 (0.976, 1.162) 0.157
Non-HDL-C, mmol/L
 < 4.1 Reference Reference Reference Reference Reference
 4.1–4.8 0.966 (0.843, 1.108) 0.621 0.988 (0.859, 1.136) 0.863 0.987 (0.858, 1.134) 0.850 0.962 (0.837, 1.107) 0.592 0.954 (0.828, 1.099) 0.516
 ≥ 4.9 1.189 (0.943, 1.500) 0.143 1.184 (0.935, 1.498) 0.160 1.175 (0.928, 1.487) 0.181 1.128 (0.890, 1.428) 0.319 1.133 (0.893, 1.438) 0.304
  1. Model 1: adjusted for age, centres
  2. Model 2: additionally adjusted for ALT, AST, GGT, eGFR
  3. Model 3: additionally adjusted for smoking, drinking, MI, stroke, CHD
  4. Model 4: additionally adjusted for BMI
  5. Model 5: additionally adjusted for HbA1c, SBP, DBP
  6. Italic values indicate significance of P value (P < 0.05)
  7. UACR: urinary albumin to creatinine ratio; TG: triglycerides; TC: total cholesterol; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; Non-HDL-C: non-high-density lipoprotein cholesterol