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Table 2 Associations between lipid parameters and UACR in the total subjects

From: Elevated triglycerides rather than other lipid parameters are associated with increased urinary albumin to creatinine ratio in the general population of China: a report from the REACTION study

Variable

Model 1

Model 2

Model 3

Model 4

Model 5

OR (95% CI)

P value

OR (95% CI)

P value

OR (95% CI)

P value

OR (95% CI)

P value

OR (95% CI)

P value

TG, mmol/L

 < 1.7

Reference

Reference

Reference

Reference

Reference

 1.7–2.2

1.125 (1.066, 1.187)

< 0.001

1.118 (1.058, 1.182)

< 0.001

1.115 (1.055, 1.179)

< 0.001

1.088 (1.029, 1.151)

0.003

1.022 (0.966, 1.081)

0.451

 ≥ 2.3

1.301 (1.229, 1.377)

< 0.001

1.274 (1.200, 1.353)

< 0.001

1.285 (1.210, 1.364)

< 0.001

1.252 (1.179, 1.330)

< 0.001

1.131 (1.065, 1.203)

< 0.001

TC, mmol/L

 < 5.2

Reference

Reference

Reference

Reference

Reference

 5.2–6.1

1.076 (1.009, 1.147)

0.026

1.056 (0.989, 1.128)

0.100

1.036 (0.970, 1.106)

0.289

1.047 (0.980, 1.118)

0.170

1.038 (0.971, 1.108)

0.274

 ≥ 6.2

1.018 (0.909, 1.140)

0.754

1.000 (0.891, 1.123)

0.996

0.950 (0.846, 1.067)

0.385

0.978 (0.871, 1.098)

0.706

0.966 (0.860, 1.086)

0.565

LDL-C, mmol/L

 < 3.4

Reference

Reference

Reference

Reference

Reference

 3.4–4.0

1.215 (1.001, 1.475)

0.049

1.230 (1.011, 1.498)

0.039

1.204 (0.989, 1.466)

0.065

1.213 (0.996, 1.477)

0.055

1.139 (0.934, 1.389)

0.199

 ≥ 4.1

1.249 (0.816, 1.912)

0.306

1.267 (0.828, 1.940)

0.276

1.238 (0.808, 1.897)

0.327

1.256 (0.820, 1.925)

0.295

1.215 (0.789, 1.870)

0.376

HDL-C, mmol/L

 ≥1.0

Reference

Reference

Reference

Reference

Reference

 < 1.0

0.958 (0.909, 1.009)

0.107

0.963 (0.909, 1.021)

0.210

0.998 (0.941, 1.058)

0.942

0.975 (0.919, 1.034)

0.403

0.952 (0.897, 1.010)

0.106

Non-HDL-C, mmol/L

 < 4.1

Reference

Reference

Reference

Reference

Reference

 4.1–4.8

1.005 (0.936, 1.080)

0.882

1.013 (0.942, 1.089)

0.735

1.029 (0.957, 1.107)

0.435

1.011 (0.940, 1.087)

0.769

0.987 (0.917, 1.062)

0.731

 ≥ 4.9

1.098 (0.975, 1.237)

0.125

1.092 (0.967, 1.233)

0.155

1.125 (0.996, 1.271)

0.058

1.092 (0.966, 1.233)

0.158

1.035 (0.916, 1.170)

0.580

  1. Model 1: adjusted for age, centres
  2. Model 2: additionally adjusted for ALT, AST, GGT, eGFR
  3. Model 3: additionally adjusted for smoking, drinking, MI, stroke, CHD
  4. Model 4: additionally adjusted for BMI
  5. Model 5: additionally adjusted for HbA1c, SBP, DBP
  6. Italic values indicate significance of P value (P < 0.05)
  7. UACR: urinary albumin to creatinine ratio; TG: triglycerides; TC: total cholesterol; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; Non-HDL-C: non-high-density lipoprotein cholesterol
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Cardiovascular Diabetology

ISSN: 1475-2840