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Table 2 Associations between lipid parameters and UACR in the total subjects

From: Elevated triglycerides rather than other lipid parameters are associated with increased urinary albumin to creatinine ratio in the general population of China: a report from the REACTION study

Variable Model 1 Model 2 Model 3 Model 4 Model 5
OR (95% CI) P value OR (95% CI) P value OR (95% CI) P value OR (95% CI) P value OR (95% CI) P value
TG, mmol/L
 < 1.7 Reference Reference Reference Reference Reference
 1.7–2.2 1.125 (1.066, 1.187) < 0.001 1.118 (1.058, 1.182) < 0.001 1.115 (1.055, 1.179) < 0.001 1.088 (1.029, 1.151) 0.003 1.022 (0.966, 1.081) 0.451
 ≥ 2.3 1.301 (1.229, 1.377) < 0.001 1.274 (1.200, 1.353) < 0.001 1.285 (1.210, 1.364) < 0.001 1.252 (1.179, 1.330) < 0.001 1.131 (1.065, 1.203) < 0.001
TC, mmol/L
 < 5.2 Reference Reference Reference Reference Reference
 5.2–6.1 1.076 (1.009, 1.147) 0.026 1.056 (0.989, 1.128) 0.100 1.036 (0.970, 1.106) 0.289 1.047 (0.980, 1.118) 0.170 1.038 (0.971, 1.108) 0.274
 ≥ 6.2 1.018 (0.909, 1.140) 0.754 1.000 (0.891, 1.123) 0.996 0.950 (0.846, 1.067) 0.385 0.978 (0.871, 1.098) 0.706 0.966 (0.860, 1.086) 0.565
LDL-C, mmol/L
 < 3.4 Reference Reference Reference Reference Reference
 3.4–4.0 1.215 (1.001, 1.475) 0.049 1.230 (1.011, 1.498) 0.039 1.204 (0.989, 1.466) 0.065 1.213 (0.996, 1.477) 0.055 1.139 (0.934, 1.389) 0.199
 ≥ 4.1 1.249 (0.816, 1.912) 0.306 1.267 (0.828, 1.940) 0.276 1.238 (0.808, 1.897) 0.327 1.256 (0.820, 1.925) 0.295 1.215 (0.789, 1.870) 0.376
HDL-C, mmol/L
 ≥1.0 Reference Reference Reference Reference Reference
 < 1.0 0.958 (0.909, 1.009) 0.107 0.963 (0.909, 1.021) 0.210 0.998 (0.941, 1.058) 0.942 0.975 (0.919, 1.034) 0.403 0.952 (0.897, 1.010) 0.106
Non-HDL-C, mmol/L
 < 4.1 Reference Reference Reference Reference Reference
 4.1–4.8 1.005 (0.936, 1.080) 0.882 1.013 (0.942, 1.089) 0.735 1.029 (0.957, 1.107) 0.435 1.011 (0.940, 1.087) 0.769 0.987 (0.917, 1.062) 0.731
 ≥ 4.9 1.098 (0.975, 1.237) 0.125 1.092 (0.967, 1.233) 0.155 1.125 (0.996, 1.271) 0.058 1.092 (0.966, 1.233) 0.158 1.035 (0.916, 1.170) 0.580
  1. Model 1: adjusted for age, centres
  2. Model 2: additionally adjusted for ALT, AST, GGT, eGFR
  3. Model 3: additionally adjusted for smoking, drinking, MI, stroke, CHD
  4. Model 4: additionally adjusted for BMI
  5. Model 5: additionally adjusted for HbA1c, SBP, DBP
  6. Italic values indicate significance of P value (P < 0.05)
  7. UACR: urinary albumin to creatinine ratio; TG: triglycerides; TC: total cholesterol; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; Non-HDL-C: non-high-density lipoprotein cholesterol