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Table 1 Characteristics of study population by UACR quartiles

From: Elevated triglycerides rather than other lipid parameters are associated with increased urinary albumin to creatinine ratio in the general population of China: a report from the REACTION study

Variable

Total

UACR quartile

P value

Q 1 (n = 8645)

Q 2 (n = 8645)

Q 3 (n = 8645)

Q 4 (n = 8634)

Age, years

57.89 ± 9.38

55.87 ± 8.67

57.07 ± 8.90

58.41 ± 9.32

60.20 ± 10.02

P < 0.001a,b,c,d,e,f

Male sex, no. (%)

11,390 (32.9)

3946 (45.6)

2779 (32.1)

2283 (26.4)

2382 (27.6)

P < 0.001

Current smoker, no. (%)

4308 (12.5)

1526 (17.7)

1054 (12.2)

827 (9.6)

901 (10.4)

P < 0.001

Current drinker, no. (%)

2394 (6.9)

803 (9.3)

563 (6.5)

531 (6.1)

497 (5.8)

P < 0.001

Previous MI, no. (%)

115 (0.3)

25 (0.3)

22 (0.3)

25 (0.3)

43 (0.5)

P = 0.021

Previous stroke, no. (%)

387 (1.1)

69 (0.8)

72 (0.8)

111 (1.3)

135 (1.6)

P < 0.001

Previous CHD, no. (%)

1127 (3.3)

190 (2.2)

261 (3.0)

269 (3.1)

407 (4.7)

P < 0.001

TG, mmol/L

1.32 (0.94, 1.32)

1.26 (0.90, 1.80)

1.30 (0.93, 1.88)

1.32 (0.95, 1.91)

1.43 (1.01, 2.09)

P < 0.001b,c,e,f

TC, mmol/L

4.99 ± 1.19

4.87 ± 1.17

4.98 ± 1.17

5.04 ± 1.19

5.07 ± 1.21

P < 0.001a,b,c,d,e

LDL-C, mmol/L

2.94 ± 0.92

2.87 ± 0.90

2.94 ± 0.91

2.97 ± 0.92

2.97 ± 0.94

P < 0.001a,b,c,e

HDL-C, mmol/L

1.30 ± 0.35

1.28 ± 0.35

1.31 ± 0.35

1.32 ± 0.35

1.28 ± 0.34

P < 0.001a,b,e,f

Non-HDL-C, mmol/L

3.69 ± 1.05

3.59 ± 1.03

3.68 ± 1.03

3.72 ± 1.05

3.78 ± 1.08

P < 0.001a,b,c,d,e,f

ALT, U/L

18.04 ± 13.91

17.98 ± 12.77

17.91 ± 13.49

17.71 ± 12.63

18.55 ± 16.36

P < 0.001c,e,f

AST, U/L

21.71 ± 12.44

21.24 ± 11.84

21.56 ± 11.04

21.58 ± 10.52

22.47 ± 15.66

P < 0.001c,e,f

GGT, U/L

28.73 ± 36.23

27.94 ± 34.17

27.49 ± 27.31

28.35 ± 37.02

31.12 ± 44.28

P < 0.001c,e,f

FBG, mmol/L

5.96 ± 1.70

5.71 ± 1.24

5.80 ± 1.40

5.95 ± 1.65

6.39 ± 2.24

P < 0.001a,b,c,d,e,f

PBG, mmol/L

8.45 ± 3.92

7.73 ± 3.15

8.06 ± 3.44

8.49 ± 3.93

9.52 ± 4.73

P < 0.001a,b,c,d,e,f

HbA1c,  %

6.08 ± 1.04

5.87 ± 0.73

5.97 ± 0.86

6.09 ± 1.04

6.37 ± 1.37

P < 0.001a,b,c,d,e,f

SBP, mmHg

131.43 ± 20.30

126.43 ± 17.69

129.39 ± 19.17

131.89 ± 20.22

138.01 ± 22.07

P < 0.001a,b,c,d,e,f

DBP, mmHg

77.47 ± 10.82

76.25 ± 10.16

76.94 ± 10.42

77.24 ± 10.75

79.44 ± 11.64

P < 0.001a,b,c,e,f

BMI, kg/m2

24.58 ± 3.66

24.36 ± 3.44

24.41 ± 3.62

24.45 ± 3.57

25.09 ± 3.96

P < 0.001c,e,f

Cr, mmol/L

67.87 ± 16.75

69.16 ± 14.02

67.06 ± 16.01

66.33 ± 16.01

68.93 ± 20.17

P < 0.001a,b,d,e,f

eGFR, ml/min per 1.73 m2

95.39 ± 21.23

97.09 ± 21.10

96.13 ± 20.23

95.55 ± 20.74

92.80 ± 22.54

P < 0.001a,b,c,e,f

  1. Data were mean ± SD or median (IQR) for skewed variables or numbers (proportions) for categorical variables
  2. UACR: urinary albumin to creatinine ratio; MI: myocardial infarction; CHD: coronary heart disease; TG: triglycerides; TC: total cholesterol; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; Non-HDL-C: non-high-density lipoprotein cholesterol; ALT: alanine aminotransferase; AST: aspartate aminotransferase; GGT: gamma-glutamyl transferase; FBG: fasting blood glucose; PBG: postprandial blood glucose; HbA1c: haemoglobin A1c; SBP: systolic blood pressure; DBP: diastolic blood pressure; BMI: body mass index; Cr: serum creatinine; eGFR: estimated glomerular filtration rate
  3. a, b, c, d, e, f: p < 0.05 for Q2 vs Q1, Q3 vs Q1, Q4 vs Q1, Q3 vs Q2, Q4 vs Q2, and Q4 vs Q3, respectively