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Table 1 Characteristics of study population by UACR quartiles

From: Elevated triglycerides rather than other lipid parameters are associated with increased urinary albumin to creatinine ratio in the general population of China: a report from the REACTION study

Variable Total UACR quartile P value
Q 1 (n = 8645) Q 2 (n = 8645) Q 3 (n = 8645) Q 4 (n = 8634)
Age, years 57.89 ± 9.38 55.87 ± 8.67 57.07 ± 8.90 58.41 ± 9.32 60.20 ± 10.02 P < 0.001a,b,c,d,e,f
Male sex, no. (%) 11,390 (32.9) 3946 (45.6) 2779 (32.1) 2283 (26.4) 2382 (27.6) P < 0.001
Current smoker, no. (%) 4308 (12.5) 1526 (17.7) 1054 (12.2) 827 (9.6) 901 (10.4) P < 0.001
Current drinker, no. (%) 2394 (6.9) 803 (9.3) 563 (6.5) 531 (6.1) 497 (5.8) P < 0.001
Previous MI, no. (%) 115 (0.3) 25 (0.3) 22 (0.3) 25 (0.3) 43 (0.5) P = 0.021
Previous stroke, no. (%) 387 (1.1) 69 (0.8) 72 (0.8) 111 (1.3) 135 (1.6) P < 0.001
Previous CHD, no. (%) 1127 (3.3) 190 (2.2) 261 (3.0) 269 (3.1) 407 (4.7) P < 0.001
TG, mmol/L 1.32 (0.94, 1.32) 1.26 (0.90, 1.80) 1.30 (0.93, 1.88) 1.32 (0.95, 1.91) 1.43 (1.01, 2.09) P < 0.001b,c,e,f
TC, mmol/L 4.99 ± 1.19 4.87 ± 1.17 4.98 ± 1.17 5.04 ± 1.19 5.07 ± 1.21 P < 0.001a,b,c,d,e
LDL-C, mmol/L 2.94 ± 0.92 2.87 ± 0.90 2.94 ± 0.91 2.97 ± 0.92 2.97 ± 0.94 P < 0.001a,b,c,e
HDL-C, mmol/L 1.30 ± 0.35 1.28 ± 0.35 1.31 ± 0.35 1.32 ± 0.35 1.28 ± 0.34 P < 0.001a,b,e,f
Non-HDL-C, mmol/L 3.69 ± 1.05 3.59 ± 1.03 3.68 ± 1.03 3.72 ± 1.05 3.78 ± 1.08 P < 0.001a,b,c,d,e,f
ALT, U/L 18.04 ± 13.91 17.98 ± 12.77 17.91 ± 13.49 17.71 ± 12.63 18.55 ± 16.36 P < 0.001c,e,f
AST, U/L 21.71 ± 12.44 21.24 ± 11.84 21.56 ± 11.04 21.58 ± 10.52 22.47 ± 15.66 P < 0.001c,e,f
GGT, U/L 28.73 ± 36.23 27.94 ± 34.17 27.49 ± 27.31 28.35 ± 37.02 31.12 ± 44.28 P < 0.001c,e,f
FBG, mmol/L 5.96 ± 1.70 5.71 ± 1.24 5.80 ± 1.40 5.95 ± 1.65 6.39 ± 2.24 P < 0.001a,b,c,d,e,f
PBG, mmol/L 8.45 ± 3.92 7.73 ± 3.15 8.06 ± 3.44 8.49 ± 3.93 9.52 ± 4.73 P < 0.001a,b,c,d,e,f
HbA1c,  % 6.08 ± 1.04 5.87 ± 0.73 5.97 ± 0.86 6.09 ± 1.04 6.37 ± 1.37 P < 0.001a,b,c,d,e,f
SBP, mmHg 131.43 ± 20.30 126.43 ± 17.69 129.39 ± 19.17 131.89 ± 20.22 138.01 ± 22.07 P < 0.001a,b,c,d,e,f
DBP, mmHg 77.47 ± 10.82 76.25 ± 10.16 76.94 ± 10.42 77.24 ± 10.75 79.44 ± 11.64 P < 0.001a,b,c,e,f
BMI, kg/m2 24.58 ± 3.66 24.36 ± 3.44 24.41 ± 3.62 24.45 ± 3.57 25.09 ± 3.96 P < 0.001c,e,f
Cr, mmol/L 67.87 ± 16.75 69.16 ± 14.02 67.06 ± 16.01 66.33 ± 16.01 68.93 ± 20.17 P < 0.001a,b,d,e,f
eGFR, ml/min per 1.73 m2 95.39 ± 21.23 97.09 ± 21.10 96.13 ± 20.23 95.55 ± 20.74 92.80 ± 22.54 P < 0.001a,b,c,e,f
  1. Data were mean ± SD or median (IQR) for skewed variables or numbers (proportions) for categorical variables
  2. UACR: urinary albumin to creatinine ratio; MI: myocardial infarction; CHD: coronary heart disease; TG: triglycerides; TC: total cholesterol; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; Non-HDL-C: non-high-density lipoprotein cholesterol; ALT: alanine aminotransferase; AST: aspartate aminotransferase; GGT: gamma-glutamyl transferase; FBG: fasting blood glucose; PBG: postprandial blood glucose; HbA1c: haemoglobin A1c; SBP: systolic blood pressure; DBP: diastolic blood pressure; BMI: body mass index; Cr: serum creatinine; eGFR: estimated glomerular filtration rate
  3. a, b, c, d, e, f: p < 0.05 for Q2 vs Q1, Q3 vs Q1, Q4 vs Q1, Q3 vs Q2, Q4 vs Q2, and Q4 vs Q3, respectively