Table 2 Models of multiple linear regression between HOMA-IR and MEEi, adjusting for kinship coefficient and subsequently for age and sex, risk factors and finally markers of inflammation
Adjusted for kinship coefficient | +Adjusted for age and sex | +Adjusted for CV risk factors | +Adjusted for markers of inflammation | |||||
|---|---|---|---|---|---|---|---|---|
Standardized β-coefficients | p≤ | Standardized β-coefficients | p≤ | Standardized β-coefficients | p≤ | Standardized β-coefficients | p≤ | |
Kinship coefficient | 0.295 | 0.0001 | 0.069 | 0.003 | 0.079 | 0.0001 | 0.087 | 0.0001 |
HOMA-IR | − 0.166 | 0.0001 | − 0.176 | 0.0001 | − 0.078 | 0.0001 | − 0.070 | 0.0001 |
Age (years) | − 0.342 | 0.0001 | − 0.236 | 0.0001 | − 0.239 | 0.0001 | ||
Sex (M/F) | 0.155 | 0.0001 | 0.130 | 0.0001 | 0.144 | 0.0001 | ||
Systolic BP (mmHg) | − 0.151 | 0.0001 | − 0.151 | 0.0001 | ||||
Cholesterol (mg/dl) | − 0.037 | 0.055 | − 0.039 | 0.042 | ||||
Triglycerides (mg/dl) | − 0.042 | 0.025 | − 0.034 | 0.069 | ||||
Waist circumference (cm) | − 0.196 | 0.0001 | − 0.156 | 0.0001 | ||||
GFRMDRD (ml/min/1.73 m2) | 0.013 | 0.462 | 0.016 | 0.357 | ||||
Fibrinogen (mg/dl) | − 0.077 | 0.0001 | ||||||
PAI-1 (ng/ml) | − 0.075 | 0.0001 | ||||||