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Table 1 Patient characteristics

From: Coronary plaque characteristics and epicardial fat tissue in long term survivors of type 1 diabetes identified by coronary computed tomography angiography

 

T1DM-patients

(n = 88)

Controls

(n = 60)

p-value*

Age (years)

61.3 ± 7.1

62.3 ± 6.8

0.38

Female, n%

47 (53.4)

34 (56.7)

0.70

Body mass index (kg/m3)

25.8 ± 3.9

25.5 ± 4.2

0.69

Waist circumference (cm)

90.3 ± 13.2

89.1 ± 12.2

0.55

Previous CVD, n%

6 (6.8)

2 (3.3)

0.36

Angina, typical

2 (2.3)

0 (0.0)

0.49

Angina, atypical

21 (24.1)

14 (23.3)

No angina

64 (73.6)

46 (76.7)

Systolic blood pressure (mmHg)

146 ± 19.8

137 ± 19.3

< 0.01

wSystolic blood pressure (mmHg)

130 ± 10.6

  

Diastolic blood pressure (mmHg)

75.3 ± 8.4

81.7 ± 9.7

< 0.01

Pulse pressure

71.6 ± 16.1

55.0 ± 14.1

< 0.01

Heart rate (bpm)

68 ± 10.3

62 ± 9.3

< 0.01

Hypertensiona, n%

23 (26.4)

11 (18.3)

0.25

Hyperlipidemiab, n%

27 (31.0)

12 (20.0)

0.17

Family history of CVD, n%

10 (11.5)

13 (21.7)

0.05

Daily smokers, n%

5 (5.7)

6 (10)

0.62

Ex-smokers, n%

34 (38.6)

22 (36.7)

pro-BNP (ng/L)

104.9 ± 110.1

67.4 ± 51.3

< 0.01

eGFR

85 ± 19.2

82 ± 12.8

0.18

Statin use, n%

40 (45.5)

6 (10.0)

< 0.01

HDL-c (mmol/L)

2.1 ± 0.5

1.8 ± 0.5

< 0.01

Statin years

2.8 ± 4.3

  

LDL-c (mmol/L)

2.8 ± 0.8

3.9 ± 1.0

 < 0.01

wLDL-c (mmol/L)

2.9 ± 0.6

  

Triglycerides (mmol/L), median (IQR)

0.77 (0.39–2.85)

0.93 (0.52–2.96)

 < 0.01

HbA1c (mmol/mol)

7.4 ± 0.81

5.4 ± 0.28

< 0.01

wHbA1c (mmol/mol)

7.9 ± 0.83

  
  1. Data are presented as mean ± SD unless otherwise stated
  2. T1DM type 1 diabetes mellitus, CVD cardiovascular disease, NT-proBNP N terminal-pro B-type natriuretic peptide, eGFR estimated glomerular filtration rate, HDL-c high density lipoprotein-cholesterol, LDL-c low density lipoprotein cholesterol, wLDL-c weighted low density lipoprotein cholesterol, HbA1c glycated hemoglobin, wHbA1c weighted glycated hemoglobin
  3. * Independent samples t-test
  4. aHypertension: previous documented hypertension in the chart or from relevant discharge letters, based on readings with sBP > 140 and/or dBP > 90
  5. bHyperlipidemia: documented hyperlipidemia or a previous total cholesterol reading of > 6.2 or LDL > 4.9 mmol/L