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Table 1 Baseline characteristics of the PROCEED study population

From: Duration of type 2 diabetes mellitus and systolic blood pressure as determinants of severity of coronary stenosis and adverse events in an asymptomatic diabetic population: PROCEED study

 

Overall population, (n = 259)

Subgroup with CTCA data, (n = 238)

Age, mean years (SD)

62.0 (8.5)

61.6 (8.6)

Sex, male (%)

151 (59)

133 (56)

BMI, median kg/m2 (IQR)

28.4 (25.3, 32.5)

28.6 (25.5, 32.6)

Ethnicity, n (%)

 African

34 (13)

33 (14)

 South Asian

142 (56)

127 (54)

 Caucasian

79 (31)

75 (32)

Duration of diabetes, median years (IQR)

13 (8, 19)

13 (8, 19)

Microvascular disease, n (%)

123 (48)

114 (48)

Retinopathy, n (%)

99 (38)

90 (38)

Hyperlipidaemia, n (%)

203 (78)

187 (79)

Hypertension, n (%)

192 (74)

176 (74)

Smoking, n (%)

20 (8)

19 (8)

Statin use, n (%)

188 (73)

173 (73)

Family history of premature ischaemic heart disease, n (%)

51 (20)

45 (19)

SBP, mm Hg (SD)

137.3 (15.8)

137.1 (15.7)

HbA1c, median mmol/mol (IQR)

63.0 (51.9, 77.0)

64.0 (51.9, 77.0)

eGFR, mean mL/min/1.73 m2 (SD)

80.9 ± 18.4

80.9 ± 18.8

CAC (AU), median (IQR)

109 (1, 322)

82 (0, 266)

Total cholesterol, mean mmol/L (SD)

4.05 (0.92)

4.08 (0.93)

LDL-C, mean mmol/L (SD)

2.10 (0.88)

2.12 (0.89)

HDL-C, mean mmol/L (SD)

1.29 (0.39)

1.29 (0.39)

Triglycerides, median mmol/L (IQR)

1.4 (0.9, 1.9)

1.4 (1.0, 1.9)

Total cholesterol:HDL-C ratio, mean (SD)

3.41 (1.2)

2.41 (1.2)

Medications for diabetes, n (%)

  

 Metformin

232 (90)

214 (90)

 Sulphonylureas

87 (34)

78 (33)

 Thiazolidinediones

21 (8)

18 (8)

 GLP-1 agonists

36 (14)

34 (14)

 DPP-4 Inhibitors

50 (19)

47 (20)

 Insulin

139 (54)

132 (55)

ACEi/ARB

163 (63)

149 (62)

  1. ACEi, angiotensin-converting enzyme inhibitor; ARB, angiotensin receptor blocker; AU, Agatston Units; BMI, body mass index; CAC, coronary artery calcium; CAD, coronary artery disease; eGFR, estimated glomerular filtration rate; HbA1c, glycated haemoglobin; HDL-C, high-density lipoprotein cholesterol; IQR, interquartile range; LDL-C, low-density lipoprotein cholesterol; SD standard deviation