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Fig. 3 | Cardiovascular Diabetology

Fig. 3

From: Altered bioavailability of epoxyeicosatrienoic acids is associated with conduit artery endothelial dysfunction in type 2 diabetic patients

Fig. 3

Type 2 diabetes profoundly impaired EETs bioavailability during endothelial stimulation. Plasma levels of epoxyeicosatrienoic acids (EETs) (a), dihydroxyeicosatrienoic acids (DHETs) (b) regioisomers and total EETs + DHETs levels (c) before (34 °C) and at the end of hand skin heating (44 °C), in healthy (n = 28), hypertensive (HT; n = 8), type 2 diabetic (T2D; n = 9) and hypertensive type 2 diabetic (HT + T2D; n = 19) subjects. Mean values ± SEM are shown. *P < 0.05, **P < 0.01. Linear relationships between the magnitude of radial artery flow-mediated dilatation with the variations in plasma EETs + DHETs during heating (d). The dashed lines represent 95% confidence interval for the regression

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Cardiovascular Diabetology

ISSN: 1475-2840