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Fig. 2 | Cardiovascular Diabetology

Fig. 2

From: Altered bioavailability of epoxyeicosatrienoic acids is associated with conduit artery endothelial dysfunction in type 2 diabetic patients

Fig. 2

Altered NO bioavailability in type 2 diabetes. Plasma levels of the NO metabolite nitrite (a) before (34 °C) and at the end of hand skin heating (44 °C) in healthy (n = 23), hypertensive (HT; n = 6), type 2 diabetic (T2D; n = 8) and hypertensive type 2 diabetic (HT + T2D; n = 18) subjects. Whole blood levels of reactive oxygen species (ROS) (b) in healthy, hypertensive (HT), type 2 diabetic (T2D) and hypertensive type 2 diabetic (HT + T2D) subjects. Mean values ± SEM are shown. *P < 0.05, **P < 0.01. Linear relationships between the magnitude of radial artery flow-mediated dilatation with the variations in plasma nitrite levels during heating (c) and with ROS levels (d). The dashed lines represent the 95% confidence interval for the regression

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Cardiovascular Diabetology

ISSN: 1475-2840