Skip to main content

Table 4 Multivariate analyses of the relationship between glycemic control and abnormal endothelial-independent and endothelial-dependent microvascular function

From: Coronary microvascular dysfunction is associated with poor glycemic control amongst female diabetics with chest pain and non-obstructive coronary artery disease

Odds ratio (95% confidence interval) Abnormal CFRAdn Ratio p value Abnormal %ΔCBFAch p value
Females
HbA1c (per unit change) 1.61 (1.07–2.40) 0.021 1.51 (1.00–2.28) 0.048
HbA1c > 7% 2.13 (0.71–6.38) 0.175 1.65 (0.55–4.95) 0.375
Glucose (per unit change) 1.02 (1.00–1.04) 0.014 1.00 (0.99–1.02) 0.846
Glucose > 140 mg/dL 4.28 (1.43–12.81) 0.009 1.54 (0.52–4.55) 0.434
Males
HbA1c (per unit change) 1.51 (0.90–2.54) 0.121 0.29 (0.09–0.92) 0.036
HbA1c > 7% 3.96 (0.62–25.14) 0.145 0.11 (0.02–0.75) 0.025
Glucose (per unit change) 1.01 (0.99–1.02) 0.423 0.99 (0.97–1.01) 0.289
Glucose > 140 mg/dL 4.16 (0.71–24.22) 0.113 0.23 (0.04–1.34) 0.101
  1. Multivariate anaylsis adjusted for the following variables: age, body mass index, smoking status, total cholesterol and systolic blood pressure at the time of catheterization
  2. CFRAdn Ratio, coronary flow reserve ratio in response to adenosine; %ΔCBFAch, percentage change in coronary blood flow in response to acetylcholine