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Table 3 Univariate analyses of the relationship between glycemic control and abnormal endothelial-independent and endothelial-dependent microvascular function

From: Coronary microvascular dysfunction is associated with poor glycemic control amongst female diabetics with chest pain and non-obstructive coronary artery disease

Odds ratio (95% confidence interval)

Abnormal CFRAdn Ratio

p value

Abnormal %ΔCBFAch

p value

Females

HbA1c (per unit change)

1.47 (1.02–2.13)

0.040

1.52 (1.02–2.27)

0.038

HbA1c > 7%

1.60 (0.59–4.38)

0.357

1.60 (0.58–4.41)

0.364

Glucose (per unit change)

1.02 (1.00–1.03)

0.035

1.01 (0.99–1.02)

0.312

Glucose > 140 mg/dL

3.36 (1.24–9.07)

0.017

1.60 (0.62–4.30)

0.340

Males

HbA1c (per unit change)

1.20 (0.84–1.72)

0.315

0.67 (0.46–1.00)

0.049

HbA1c > 7%

1.77 (0.47–6.62)

0.397

0.29 (0.08–1.03)

0.056

Glucose (per unit change)

1.00 (0.98–1.01)

0.527

0.99 (1.00–1.01)

0.111

Glucose > 140 mg/dL

1.37 (0.39–4.89)

0.625

0.39 (0.11–1.29)

0.125

  1. CFRAdn Ratio, coronary flow reserve ratio in response to adenosine; %ΔCBFAch, percentage change in coronary blood flow in response to acetylcholine