Table 1 Baseline characteristics and treatment allocation of IVUS sub-study population (n = 56)

Demographics

 Patient age (years)

60.0 ± 8.0

 Female gender (%)

12 (21)

 Duration of T2D (years)

5.9 ± 5.7

Hemodynamics

 Systolic blood pressure (mmHg)

139.4 ± 18.6

 Diastolic blood pressure (mmHg)

81.6 ± 9.3

Angiographic findings

 Normal

21 (38%)

 Wall changes

17 (30%)

 25–50% stenosis

4 (7%)

 > 50% stenosis

14 (25%)

Biochemistry

 Hba1c (%)

7.5 ± 1.6

 Total cholesterol (mmol/L)

5.0 ± 1.0

 Triglycerides (mmol/L)

1.7 ± 1.0

 HDL-cholesterol (mmol/L)

1.3 ± 0.4

 LDL-cholesterol (mmol/L)

2.9 ± 0.9

 Microalbuminuria

26.2 ± 40.8

 eGFR (mL/min/1.73 m²)(MDRD)

91.8 ± 19.2

 hsCRP (mg/l)^a

0.23 ± 0.34

 NT-proBNP (ng/L)^b

8.6 ± 14.2

Medication

 Any oral antidiabetic medication (%)

42 (75%)

 Insulin

8 (14%)

 Loop/thiazide diuretic (%)

8 (14%)

 ACE inhibitor (%)

9 (16%)

 ARB (%)

13 (23%)

 Statin therapy (%)

28 (50%)

 Acetyl salicylic acid (%)

17 (30%)

Treatment allocated

 Multi-intervention strategy

30 (53%)

 Conventional therapy

26 (46%)