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Fig. 8 | Cardiovascular Diabetology

Fig. 8

From: Pioglitazone strengthen therapeutic effect of adipose-derived regenerative cells against ischemic cardiomyopathy through enhanced expression of adiponectin and modulation of macrophage phenotype

Fig. 8

Gene and protein expression in the heart. a Quantitative RT-PCR results for the expression levels of APN, CDH-13, Adipo-R1, Adipo-R2, SDF-1, VEGF, HGF, TNF-α, IL-6 and IL-10 genes in the infarct border area. APN was significantly higher in the ADRC groups than in the C group. ADRCs effect on VEGF and HGF expression after myocardial infarction during the early days of implantation. b Representative immunoblot of T-cadherin in total protein extracted from the heart 3 days and 8 weeks after implantation. c T-cadherin expression levels were higher in the A and AP groups than in the C and Si groups during the early days after implantation. At 8 weeks, T-cadherin levels were higher in the AP group than in the other groups. Multiple comparisons were made by one-way ANOVA. n = 8–10; *P < 0.05 versus C group, **P < 0.05 versus A group, †P < 0.05 versus Si group

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