Fig. 2From: Pioglitazone strengthen therapeutic effect of adipose-derived regenerative cells against ischemic cardiomyopathy through enhanced expression of adiponectin and modulation of macrophage phenotypeRelationship between implanted graft and ischemic heart. The ADRCs and PGZ in graft was implanted on the surface of the heart. PGZ is thought to act on the cells in graft, pericardial adipocyte and residual cardiomyocytes, and enhance the APN production in these cells. Furthermore factors that affect the phenotypical change of macrophage and characteristics of these macrophage are shownBack to article page