Fig. 3

Analysis of a HbA1c b urine glucose levels, c urine creatine and d urine glucose/creatinine during the study. In the  treated group (n = 22) HbA1c decreased, increased in ob/ob^−/− untreated group (n = 21), and did not change in lean controls (n = 12) compared with baseline levels. Data were analyzed using repeated measure Anova with Tukey’s multiple comparisons test and are presented as mean with 95% confidence interval. *p < 0.05 and **p < 0.01 represents significant difference between lean controls and ob/ob^−/− groups. ^‡p ≤ 0.05 for ob/ob^−/− treated and untreated group